A multi-method assessment of treatment adherence for children with cystic fibrosis
A multi-method assessment of treatment adherence for children with cystic fibrosis
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DOI：
10.1016/j.jcf.2006.03.002
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发表时间：
2006-08-01
影响因子：
5.2
通讯作者：
Quittner, Alexandra L.
中科院分区：
文献类型：
--
作者：
Modi, Avani C.;Lim, Crystal S.;Quittner, Alexandra L.
背景：慢性儿科疾病的依从率约为50%。本研究的主要目的是评估率的坚持使用四种不同的测量方法为儿童囊性纤维化（CF）。方法：参与者包括37名儿童与CF之间的6至13岁，他们的主要照顾者。依从性措施包括父母和孩子的自我报告，日记数据，药房再填充的历史，和电子monitors.Results：结果表明，遵守率各不相同的治疗组成部分和跨测量方法。然而，当检查更客观的指标时，CF儿童的总体依从性低于50%，表明对治疗方案的依从性普遍较差。例如，使用电子和日记测量的酶药物依从率范围为27%至46%。结论：多方法测量方法提供了关于每种疾病治疗成分类型依从率的独特信息。准确测量CF儿童的治疗依从率是制定有效干预措施以影响这些行为的重要一步。(C)2006年欧洲囊性纤维化协会。Elsevier B.V.出版，保留所有权利。
Background: Adherence rates for chronic pediatric conditions are approximately 50%. The primary objective of the study was to assess rates of adherence using four different measurement methods for children with cystic fibrosis (CF).Methods: Participants included 37 children with CF between 6 and 13 years of age and their primary caregivers. Adherence measures included parent and child self-reports, diary data, pharmacy refill history, and electronic monitors.Results: Results suggested that rates of adherence varied by treatment component and across measurement methods. However, when examining more objective measures, rates of overall adherence were below 50% for children with CF, indicating generally poor adherence to the treatment regimen. For example, rates of adherence to enzyme medications, using electronic and diary measures, ranged from 27% to 46%.Conclusions: The multi-method measurement approach provided unique information regarding rates of adherence for each disease condition by type of treatment component. Accurately measuring rates of treatment adherence for children with CF is an important step in developing effective interventions to influence these behaviors. (C) 2006 European Cystic Fibrosis Society. Published by Elsevier B.V. All rights reserved.