Impact of Scanning Density on Measurements from Spectral Domain Optical Coherence Tomography
Impact of Scanning Density on Measurements from Spectral Domain Optical Coherence Tomography
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DOI：
10.1167/iovs.09-4325
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发表时间：
2010-02-01
影响因子：
4.4
通讯作者：
Walsh, Alexander C.
中科院分区：
文献类型：
--
作者：
Sadda, Srinivas R.;Keane, Pearse A.;Walsh, Alexander C.
目的.探讨视网膜病变患者B超密度与光谱域光学相干断层扫描（SDOCT）测量视网膜厚度的关系。数据收集自115名使用Cirrus HD-OCT进行容积OCT成像的患者，采用512 x 128水平光栅方案。原始OCT数据，包括自动视网膜边界的位置，从Cirrus HD-OCT仪器导出并导入Doheny图像阅读中心（DIRC）OCT查看和分级软件，称为“3D-OCTOR”。“对于每种情况，使用所有128次B扫描以及使用密度较低的扫描子集（从每隔一次扫描到每16次扫描）生成类似于Cirrus HD-OCT生成的视网膜厚度图。将仅使用一部分扫描获得的视网膜厚度测量值与使用所有128个B扫描获得的测量值进行比较，并计算中心凹中央子场（FCS）和总黄斑体积的差异。FCS视网膜厚度测量的平均误差随B超密度的降低而增大，但误差较小（
PURPOSE. To investigate the relationship between B-scan density and retinal thickness measurements obtained by spectral domain optical coherence tomography (SDOCT) in eyes with retinal disease.METHODS. Data were collected from 115 patients who underwent volume OCT imaging with Cirrus HD-OCT using the 512 x 128 horizontal raster protocol. Raw OCT data, including the location of the automated retinal boundaries, were exported from the Cirrus HD-OCT instrument and imported into the Doheny Image Reading Center (DIRC) OCT viewing and grading software, termed "3D-OCTOR." For each case, retinal thickness maps similar to those produced by Cirrus HD-OCT were generated using all 128 B-scans, as well as using less dense subsets of scans, ranging from every other scan to every 16th scan. Retinal thickness measurements derived using only a subset of scans were compared to measurements using all 128 B-scans, and differences for the foveal central subfield (FCS) and total macular volume were computed.RESULTS. The mean error in FCS retinal thickness measurement increased as the density of B-scans decreased, but the error was small (