Development of Apatite Nuclei Precipitated Carbon Nanotube-Polyether Ether Ketone Composite with Biological and Electrical Properties
Development of Apatite Nuclei Precipitated Carbon Nanotube-Polyether Ether Ketone Composite with Biological and Electrical Properties
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DOI：
10.3390/coatings10020191
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发表时间：
2020-02-01
期刊：
影响因子：
3.4
通讯作者：
Takai, Shigeomi
中科院分区：
文献类型：
--
作者：
Ishizaki, Chihiro;Yabutsuka, Takeshi;Takai, Shigeomi
我们的目标是赋予碳纳米管(CNT)-聚醚醚酮(PEEK)复合材料(CNT-PEEK)形成磷灰石的能力。由于碳纳米管具有导电性，碳纳米管聚醚醚酮不仅可用于植入材料，还可用于生物传感设备。首先，在本研究中，用硫酸对CNT-PEEK进行表面处理，使其表面形成细孔。然后，通过氧等离子体处理提高了基材的亲水性。然后，将基质迅速浸泡在模拟体液(SBF)中，模拟体液(SBF)被调节到pH 8.40，25.0℃(碱性SBF)，并在70.0℃的孵化器中保持1天，以沉积细小的无定形磷酸钙颗粒，我们将其称为“磷灰石核”。将处理后的CNT-PEEK浸泡在SBF中，1d内其表面就能自发地被沉积在细孔中的磷灰石核所覆盖，并显示出较高的磷灰石形成能力。经过上述处理后的CNT-PEEK也表现出了导电性，并且表现出比未经处理的CNT-PEEK衬底更小的阻抗。
We aimed to impart apatite-forming ability to carbon nanotube (CNT)-polyether ether ketone (PEEK) composite (CNT-PEEK). Since CNT possesses electrical conductivity, CNT-PEEK can be expected to useful not only for implant materials but also biosensing devices. First of all, in this study, CNT-PEEK was treated with sulfuric acid to form fine pores on its surface. Then, the hydrophilicity of the substrate was improved by oxygen plasma treatment. After that, the substrate was promptly immersed in simulated body fluid (SBF) which was adjusted at pH 8.40, 25.0 degrees C (alkaline SBF) and held in an incubator set at 70.0 degrees C for 1 day to deposit fine particles of amorphous calcium phosphate, which we refer to as 'apatite nuclei'. When thus-treated CNT-PEEK was immersed in SBF, its surface was spontaneously covered with hydroxyapatite within 1 day by apatite nuclei deposited in the fine pores and high apatite-forming ability was successfully demonstrated. The CNT-PEEK also showed conductivity even after the above treatment and showed smaller impedance than that of the untreated CNT-PEEK substrate.