Submicroscopic structure of the membranous labyrinth
Submicroscopic structure of the membranous labyrinth
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膜迷路的亚显微结构
DOI：
10.1007/bf00326848
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
S. Iurato
中科院分区：
文献类型：
--
作者：
S. Iurato
通过光学和电子显微镜对基底膜、螺旋缘和螺旋韧带进行研究。这些不同的部分相互延续，构成一个单一的形态和功能结构，可称为“柯蒂氏器官的支撑结构”(s.s.C.o.)。它是由以细胞为成分的组织和其中排列有毛细血管的细胞间质形成的。细胞可分为两组，第一组由固有细胞（基底膜、螺旋缘和螺旋韧带细胞），其结构变化与细胞间质的生长机制平行；耳蜗管的第二部分覆盖细胞（柯蒂氏器细胞、内外螺旋沟细胞、齿间细胞、血管纹细胞）。细胞间质以薄层、纤维层、束和微观纤维的形式组织，由细丝和介入的基质组成。细丝的直径范围为 85 至 105 Å。偏光显微镜的拓扑化学测试、酶测试、衍射和化学分析表明，这些丝毫无疑问由与胶原蛋白或弹性纤维无关的蛋白质材料组成。也许它可以归入 K.E.M.F. 类别。基质通常呈现无组织且透明，但在基底膜的某些部分呈现棉花状外观。关于 s.s.C.o 分类的可能不同假设。基底膜、螺旋缘和螺旋韧带中的细胞和细胞间质的数量和结构有明显差异，逐一详细检查。由具有含有丝状硬化蛋白的细胞间质的组织形成，清楚地证实了柯蒂氏器官执行支持活性的理论。术语“柯蒂氏器的支撑结构”就是基于这种解释。
Investigations were performed by light and electron microscope on the basilar membrane, limbus spiralis and spiral ligament.These different parts continue one into the other and make up a single morphological and functional structure which may be called the “supporting structure ofCorti's organ” (s.s.C.o.).It is formed by a tissue the components of which are the cells and an intercellular substance in which are arranged the capillary vessels.The cells can be classed in two groups, the first consisting of the cells proper (basilar membrane, limbus spiralis and spiral ligament cells) which present structural changes parallel with the growth mechanism of the intercellular substance; the second of the cochlear duct covering cells (Corti's organ cells, inner and outer spiral sulcus cells, interdental cells, stria vascularis cells).The intercellular substance is organised in laminae, fibrolaminae, bundles and microscopic fibers composed of filaments with an intervening ground substance.The filaments have a diameter ranging from 85 to 105 Å. Topochemical tests with polarised light microscope, enzymatic tests, diffractographic and chemical analyses suggest that these filaments unquestionably consist of protein material which have nothing to do with collagen or elastic fibers. Perhaps it may be classed in the K.E.M.F. group.The ground substance generally appear anhistous and transparent but in some parts of the basilar membrane it presents a cottony appearance.The possible different hypotheses about the classification of the s.s.C.o. tissue are discussed.The quantity and architecture of the cells and the intercellular substance vary appreciably in the basilar membrane, limbus spiralis and spiral ligament, which are examined in detail one by one.The demonstration that the s.s.C.o. is formed of a tissue possessing an intercellular substance containing filamentous scleroproteins clearly corroborates the theory that is performs supporting activity in respect ofCorti's organ. The term “supporting structure ofCorti's organ” is based on this interpretation.