Production of levulinic acid and use as a platform chemical for derived products
Production of levulinic acid and use as a platform chemical for derived products
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DOI：
10.1016/s0921-3449(99)00047-6
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发表时间：
2000-02-01
影响因子：
13.2
通讯作者：
Jarnefeld, JL
中科院分区：
文献类型：
--
作者：
Bozell, JJ;Moens, L;Jarnefeld, JL
乙酰丙酸（LA）可以在一种新的工业过程中从可再生原料中以高收率和低成本生产。该技术正在纽约南格伦斯福尔斯的一个设施以1吨/天的规模进行示范。低成本的LA可用作生产各种增值产品的平台化学品。这项研究表明，LA可以转化为甲基四氢呋喃（MTHF），溶剂和燃料增量剂。MTHF通过单阶段催化氢化工艺以>80%摩尔产率生产。还开发了一种由LA制备广谱除草剂δ-氨基乙酰丙酸（DALA）的新方法。该新方法中的每个步骤都以高（> 80%）产率进行，并以> 90%的纯度提供DALA（作为盐酸盐），从而得到商业上可行的方法。LA还被研究作为生产双酚酸（DPA）的起始材料，双酚酸是双酚A的直接替代品。(C)由Elsevier Science B. V.出版，版权所有。
Levulinic acid (LA) can be produced cost effectively and in high yield from renewable feedstocks in a new industrial process. The technology is being demonstrated on a I ton/day scale at a facility in South Glens Falls, New York. Low cost LA can be used as a platform chemical for the production of a wide range of value-added products. This research has demonstrated that LA can be converted to methyltetrahydrofuran (MTHF), a solvent and fuel extender. MTHF is produced in >80% molar yield via a single stage catalytic hydrogenation process. A new preparation of delta-aminolevulinic acid (DALA), a broad spectrum herbicide, from LA has also been developed. Each step in this new process proceeds in high (> 80%) yield and affords DALA (as the hydrochloride salt) in > 90% purity, giving a process that could be commercially viable. LA is also being investigated as a starting material for the production of diphenolic acid (DPA), a direct replacement for bisphenol A. (C) 2000 ACEEE Published by Elsevier Science B.V. All rights reserved.