CLINICAL OBSERVATIONS IN TYPHUS FEVER: WITH SPECIAL REFERENCE TO THE CARDIOVASCULAR SYSTEM
CLINICAL OBSERVATIONS IN TYPHUS FEVER: WITH SPECIAL REFERENCE TO THE CARDIOVASCULAR SYSTEM
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斑疹伤寒的临床观察：特别关注心血管系统
DOI：
10.1001/jama.1944.02850400019006
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发表时间：
1944
期刊：
影响因子：
--
通讯作者：
E. Bland
中科院分区：
文献类型：
--
作者：
T. Woodward;E. Bland
本研究主要是为了观察斑疹伤寒发生的各种生理变化，特别关注大循环的状态。以前对该疾病的描述经常提到心脏衰竭、心力衰竭或心脏无力，在斑疹伤寒流行的地区，服用洋地黄、哇巴因或其他替代品形式的心脏兴奋剂几乎是一种常规程序。同样，在某些部分，由于患者的身体极度虚弱且有毒，因此会给予强心药物，并认为这些强心剂会改善血液循环。后者与洋地黄的实际生理作用并不相符，Luten 1已表明洋地黄和具有洋地黄样作用的药物的唯一临床适应症是“心力衰竭的证据”和某些心律失常。在我们的研究中，没有明确的心脏病迹象
This study was undertaken principally to observe the various physiologic changes occurring in typhus fever with special attention directed to the status of the general circulation. Previous descriptions of the disease frequently refer to cardiac collapse, cardiac failure or cardiac weakness and in areas where typhus is prevalent it is almost a routine procedure to administer cardiac stimulants in the form of digitalis, ouabain or perhaps some other substitute. Likewise, in certain sections cardiac drugs are given because of the extremely weak and toxic appearance of the patient with the thought in mind that these cardiac tonics will improve the circulation. The latter is not in accord with the actual physiologic effect of digitalis, and Luten 1 has shown that the only clinical indication for digitalis and drugs with digitalis-like action is "evidence of cardiac failure" and in certain arrhythmias. In our study there was no clear indication for cardiac