Evaluation of enhanced recovery after surgery program components implemented in laparoscopic appendectomy: prospective randomized clinical study
Evaluation of enhanced recovery after surgery program components implemented in laparoscopic appendectomy: prospective randomized clinical study
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DOI：
10.1038/s41598-020-67591-5
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发表时间：
2020-07-01
影响因子：
4.6
通讯作者：
Tyagunov, Anton
中科院分区：
文献类型：
--
作者：
Nechay, Taras;Sazhin, Alexander;Tyagunov, Anton
背景腹腔镜阑尾切除术（LA）是一种应用广泛的外科手术。患者往往遭受相当大的术后疼痛和消化不良，这延长了他们的住院时间。近10%的患者出现术后并发症。手术后增强恢复（ERAS）计划已被证明其在选择性手术中的有效性，并且可以假设改善LA结果。目前，洛杉矶没有ERAS项目。方法采用前瞻性、随机、非盲法临床试验，研究改进的ERAS （mERAS）方案。mERAS组包括50例患者；对照组54例。mERAS方案包括患者信息手册；尽量减少排水渠的使用；局部麻醉;低压气腹;早期动员和口服饮食。主要观察指标为术后住院时间（pLOS）。结果：修改后的方案将pLOS的中位时间缩短至1.25天，而对照组为2天
BackgroundLaparoscopic appendectomy (LA) is a widely used surgical procedure. Patients often suffer from considerable postoperative pain and indigestion, which prolongs their in-hospital stay. Almost 10% of patients develop postoperative complications. The enhanced recovery after surgery (ERAS) program has proven its efficacy in elective surgery and could hypothetically improve LA outcomes. Currently, there is no ERAS program for LA.Methods A modified ERAS (mERAS) protocol was studied in a prospective, randomized nonblinded clinical trial. The mERAS group consisted of 50 patients; the control group, of 54 patients. The mERAS protocol included a patient information brochure; minimizing drain use; local anesthesia; low-pressure pneumoperitoneum; early mobilization and oral diet. The primary outcome was postoperative length of stay (pLOS).Results Modified protocol reduced median pLOS to 1.25 days vs 2 days in the controls (p