Rapid microwave-promoted Suzuki cross coupling reaction in water
Rapid microwave-promoted Suzuki cross coupling reaction in water
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DOI：
10.1039/b305191a
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发表时间：
2003-01-01
期刊：
影响因子：
9.8
通讯作者：
Zhang, YM
中科院分区：
文献类型：
--
作者：
Bai, L;Wang, JX;Zhang, YM
水是一种廉价无毒的反应介质，用于微波促进的芳基硼酸与芳基卤化物的Suzuki偶联反应。这种环境友好的微波方案提供了方便的操作和合成各种取代的联芳基化合物的高产率非常迅速，使用PdCl 2（PPh3）（2）作为催化剂和碳酸钾作为碱。
Water is an inexpensive and nontoxic reaction medium for the microwave-promoted Suzuki cross coupling of arylboronic acids with aryl halides. This environmentally friendly microwave protocol offers convenient operation and synthesis of a variety of substituted biaryls in good yield very rapidly employing PdCl2(PPh3)(2) as catalyst and potassium carbonate as the base.