A highly efficient low temperature modification of the classical Ullmann reaction
A highly efficient low temperature modification of the classical Ullmann reaction
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DOI：
10.2174/157017806779467979
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发表时间：
2006-12-01
影响因子：
0.8
通讯作者：
Nicod, Nathalie
中科院分区：
文献类型：
--
作者：
Leroux, Fredric R.;Simon, Roger;Nicod, Nathalie
The efficient synthesis of sterically demanding tetra-substituted biaryls by means of a one-pot three-step low-temperature modification of the classical Ullmann reaction is reported. The major benefit of this methodology lies in the ready synthesis of polybrominated biaryls, which can be subsequently functionalized into various target molecules by means of regioselective halogen/metal permutations.
