Recurrent and de novo glomerular disease after renal transplantation - A report from Renal Allograft Disease Registry (RADR)

Recurrent and de novo glomerular disease after renal transplantation - A report from Renal Allograft Disease Registry (RADR)
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DOI:
10.1097/00007890-199909150-00007
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发表时间:
1999-09-15
期刊:
影响因子:
6.2
通讯作者:
George, V
George, V
中科院分区:
医学2区
文献类型:
--
作者:
Hariharan, S;Adams, MB;George, V

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导论.在过去的15年里,肾移植的短期和长期结果都有所改善。然而,复发和新发疾病的流行率没有变化。通过肾移植疾病登记处发起了一项回顾性研究,以评估移植后复发和新发疾病的患病率和影响。从1987年10月至1996年12月,在威斯康星州医学院、辛辛那提大学、加州大学弗朗西斯科分校、路易斯维尔大学、华盛顿大学西雅图分校和华盛顿大学医学院共进行了4913例成人肾移植。患者随访至少1年。167例(3.4%)经肾活检确诊为复发和新发疾病。将这些患者与其他没有复发和新发疾病的患者(n=4746)进行比较。男性多于女性(67.7%比59.8%,P
Introduction. Short-term and long-term results of renal transplantation have improved over the past 15 years. However, there has been no change in the prevalence of recurrent and de novo diseases. A retrospective study was initiated through the Renal Allograft Disease Registry, to evaluate the prevalence and impact of recurrent and de novo diseases after transplantation.Materials and Methods. From October 1987 to December 1996, a total of 4913 renal transplants were performed on adults at the Medical College of Wisconsin, University of Cincinnati, University of California at San Francisco, University of Louisville, University of Washington, Seattle, and Washington University School of Medicine. The patients were followed for a minimum of 1 year. A total of 167 (3.4%) cases of recurrent and de novo disease were diagnosed by renal biopsy. These patients were compared with other patients who did not have recurrent and de novo disease (n=4746). There were more men (67.7% vs, 59.8%, P