A nonlinear elasticity phantom containing spherical inclusions.
A nonlinear elasticity phantom containing spherical inclusions.
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DOI：
10.1088/0031-9155/57/15/4787
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发表时间：
2012-08-07
影响因子：
3.5
通讯作者：
Hall TJ
中科院分区：
文献类型：
--
作者：
Pavan TZ;Madsen EL;Frank GR;Jiang J;Carneiro AA;Hall TJ
一些在体乳腺病变的应变图像对比度随着施加载荷的增加而变化。这种变化归因于组成组织的非线性弹性性质的差异，这表明通过其非线性弹性性质来帮助对乳腺疾病进行分类的一些潜力。一个幻影夹杂物和长期稳定性，希望作为非线性弹性成像方法的开发，测试等的测试平台。本研究报告的幻影设计调查非线性弹性特性与超声弹性成像技术。体模包含四个球形内含物，由明胶、琼脂和油的混合物制成。体模背景和每个夹杂物具有不同的杨氏模量和非线性力学行为。该体模进行大变形（高达20%），同时用超声扫描，应变图像对比度和对比噪声比（CNR）的变化夹杂物和背景之间，作为应用变形的函数，进行了研究。对比度的变化在一个大的变形范围内预测的有限元分析（FEA）与实验观察到的一致。因此，该论文报告了一种基于组成材料的独立测量来制作具有可预测的非线性行为的幻影的方法，并表明所得到的应变图像（例如，应变对比）与非线性有限元分析预测的结果一致。
The strain image contrast of some in vivo breast lesions changes with increasing applied load. This change is attributed to differences in the nonlinear elastic properties of the constituent tissues suggesting some potential to help classify breast diseases by their nonlinear elastic properties. A phantom with inclusions and long-term stability is desired to serve as a test bed for nonlinear elasticity imaging method development, testing, etc. This study reports a phantom designed to investigate nonlinear elastic properties with ultrasound elastographic techniques. The phantom contains four spherical inclusions and was manufactured from a mixture of gelatin, agar and oil. The phantom background and each of the inclusions has distinct Young’s modulus and nonlinear mechanical behavior. This phantom was subjected to large deformations (up to 20%) while scanning with ultrasound, and changes in strain image contrast and contrast-to-noise ratio (CNR) between inclusion and background, as a function of applied deformation, were investigated. The changes in contrast over a large deformation range predicted by the finite element analysis (FEA) were consistent with those experimentally observed. Therefore, the paper reports a procedure for making phantoms with predictable nonlinear behavior, based on independent measurements of the constituent materials, and shows that the resulting strain images (e.g., strain contrast) agrees with that predicted with nonlinear FEA.
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影响因子：
3.5
作者：
O'Hagan, Joseph J.;Samani, Abbas
通讯作者：
Samani, Abbas
影响因子：
56.9
作者：
MUTHUPILLAI, R;LOMAS, DJ;EHMAN, RL
通讯作者：
EHMAN, RL
DOI：
10.1109/tuffc.2004.1320826
发表时间：
2004-05-01
影响因子：
3.6
作者：
Erkamp, RQ;Emelianov, SY;O'Donnell, M
通讯作者：
O'Donnell, M
影响因子：
2.3
作者：
Kallel, F;Ophir, J
通讯作者：
Ophir, J
影响因子：
2.9
作者：
Jiang, Jingfeng;Hall, Timothy J.;Sommer, Amy M.
通讯作者：
Sommer, Amy M.