Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital

Primary malignant neoplasms of orofacial origin: a retrospective review of 256 cases in a Nigerian tertiary hospital
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DOI:
10.1016/j.ijom.2007.01.007
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发表时间:
2007-05-01
影响因子:
2.4
通讯作者:
Arotiba, G. T.
Arotiba, G. T.
中科院分区:
医学3区
文献类型:
--
作者:
Ajayi, O. F.;Adeyemo, W. L.;Arotiba, G. T.

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回顾性分析了1992-2003年尼日利亚拉各斯大学教学医院口腔病理学和生物学系记录的经组织学诊断为口面部恶性病变的病例。对所有病例进行年龄、性别、部位分布及组织学类型分析。恶性肿瘤占18%的所有活组织检查的口面部病变看到的时期内。患者的平均年龄为42.2 ± 21.5岁(范围:2.5-85岁)。上皮性肿瘤177例(69%),其中以鳞状细胞癌为主,肉瘤47例(18%),淋巴瘤32例(13%)。鳞状细胞癌(44%)是最常见的口腔颌面部恶性肿瘤。骨肉瘤(32%)和Burkitt淋巴瘤(56%)分别是主要的肉瘤和淋巴瘤。组织学诊断为癌的患者年龄大于肉瘤和淋巴瘤(P
A retrospective review of cases histologically diagnosed as malignant lesions of the orofacial region in 1992-2003 from the records of the Department of Oral Pathology and Biology, Lagos University Teaching Hospital, Nigeria was carried out. All cases were subjected to analysis of age, gender, site distribution and histologic types. Malignant tumours constituted 18% of all the biopsies of orofacial lesions seen within the period. The mean age of patients was 42.2 +/- 21.5 years (range: 2.5-85). There were 177 (69%) epithelial tumours of which squamous cell carcinoma was predominant, 47 (18%) sarcomas and 32 (13%) lymphomas. Squamous cell carcinoma (44%) was the most common malignant orofacial tumour. Osteosarcoma (32%) and Burkitt's lymphoma (56%) was the predominant sarcoma and lymphoma, respectively. Patients with a histologic diagnosis of carcinoma were older than those with sarcomas and lymphomas (P