Antimicrobial indole alkaloids with adductive C9 aromatic unit from Gelsemium elegans
Antimicrobial indole alkaloids with adductive C9 aromatic unit from Gelsemium elegans
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DOI：
10.1016/j.tetlet.2018.04.041
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发表时间：
2018-05-23
影响因子：
1.8
通讯作者：
Luo, Xiao-Dong
中科院分区：
文献类型：
--
作者：
Wei, Xin;Yang, Jing;Luo, Xiao-Dong
从钩吻中分离得到3个新的含9个碳原子侧链的钩吻碱类化合物，即钩吻碱A-C（1-3）。通过光谱技术和电子圆二色谱（ECD）计算确定了它们的结构。此外，gelselegandines A-C对四种细菌菌株和两种真菌显示出中等的抗微生物活性。(C)2018爱思唯尔有限公司版权所有
Gelselegandines A-C (1-3), three unprecedented gelsedines incorporating additional C-9 aromatic unit as side chain, were isolated from Gelsemium elegans. Their structures were elucidated by means of spectroscopic techniques and electronic circular dichroism (ECD) calculation. Additionally, gelselegandines A-C showed moderate antimicrobial activities against four bacterial strains and two fungi. (C) 2018 Elsevier Ltd. All rights reserved.