Efficacy of Mirtazapine on Irritable Bowel Syndrome with Anxiety and Depression: A Case Study
Efficacy of Mirtazapine on Irritable Bowel Syndrome with Anxiety and Depression: A Case Study
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DOI：
10.1272/jnms.jnms.2018_85-53
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发表时间：
2018-12-01
影响因子：
1
通讯作者：
Matsumoto, Hideo
中科院分区：
文献类型：
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作者：
Akama, Fumiaki;Mikami, Katsunaka;Matsumoto, Hideo
肠易激综合征（IBS）是一种胃肠道疾病，主要是腹痛或不适和排便异常长期持续存在。对于IBS患者，精神疾病，特别是抑郁和/或焦虑，导致生活质量进一步降低。本个案研究的目的是探讨米氮平（MIR）对伴有焦虑和抑郁状态的IBS病例的心理健康和IBS症状的影响。此病例报告表明，MIR是有效的治疗肠易激综合征的主要腹泻伴随抑郁和焦虑。
Irritable bowel syndrome (IBS) is a disease in which gastrointestinal symptoms-primarily abdominal pain or discomfort and abnormal bowel movements persist chronically. For patients with IBS, mental illness, especially depression and/or anxiety, leads to a further lower quality of life. The purpose of this case study was to investigate the effects of mirtazapine (MIR) on mental health and IBS symptoms in a case of IBS accompanied by anxiety and a depressive state. This case report suggests that MIR is efficacious for the treatment of IBS with predominant diarrhea accompanied by depression and anxiety.