Relationships Between Pain, Life Stress, Sociodemographics, and Cortisol: Contributions of Pain Intensity and Financial Satisfaction.
Relationships Between Pain, Life Stress, Sociodemographics, and Cortisol: Contributions of Pain Intensity and Financial Satisfaction.
复制标题
疼痛，生命压力，社会数字学和皮质醇之间的关系：疼痛强度和经济满意度的贡献。
DOI：
10.1177/2470547020975758
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发表时间：
2020-01
期刊：
影响因子：
--
通讯作者：
Sibille KT
中科院分区：
文献类型：
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作者：
Mickle AM;Garvan C;Service C;Pop R;Marks J;Wu S;Edberg JC;Staud R;Fillingim RB;Bartley EJ;Sibille KT
心理社会压力和慢性疼痛之间的关系是双向的。对慢性疼痛、生活压力和种族/人种之间关系的进一步了解将有助于识别导致慢性疼痛健康差异的因素，并改善健康结局。本研究旨在评估临床疼痛、生活压力、社会人口统计学和唾液皮质醇水平之间的关系。一项横断面分析，涉及105名45-85岁的非西班牙裔白色（NHW）和非西班牙裔黑人（NHB）参与者的数据，这些参与者患有膝关节骨关节炎或有膝关节骨关节炎风险。数据包括在大约12小时内的5个时间点的社会人口统计学、临床疼痛、心理社会压力和唾液皮质醇。进行非参数相关分析、社会人口统计学组比较和回归分析。临床疼痛和心理社会压力与唾液皮质醇水平相关，特别是早晨醒来和晚上到早晨醒来的斜率。纳入公认的解释变量，分级慢性疼痛量表特征疼痛强度和经济满意度被确定为主要的疼痛和心理社会措施与皮质醇水平。社会人口群体差异表明，NHB参与者报告更高的疼痛相关的残疾，更高的歧视水平，更低的经济和物质满意度，并显示出更高的夜间唾液皮质醇水平相比，NHW参与者。在结合疼痛和心理社会压力分析，更大的经济满意度，较低的疼痛强度，和较低的抑郁与较高的早晨醒来唾液皮质醇水平，而更大的经济满意度是唯一的变量与更大的晚上到早晨醒来的斜率。我们的研究结果显示了临床疼痛，心理社会压力，社会人口因素和唾液皮质醇水平之间的关系。重要的是，包括公认的解释变量，财务满意度仍然是主要因素，解释不同的早晨醒来的皮质醇和晚上到早晨醒来的皮质醇斜率在一个种族/种族多样化的中年和老年人组或膝关节骨关节炎的风险。
The relationship between psychosocial stress and chronic pain is bidirectional. An improved understanding regarding the relationships among chronic pain, life stress, and ethnicity/race will inform identification of factors contributing to health disparities in chronic pain and improve health outcomes. This study aims to assess relationships between measures of clinical pain, life stress, sociodemographics, and salivary cortisol levels. A cross-sectional analysis involving data from 105 non-Hispanic White (NHW) and non-Hispanic Black (NHB) participants aged 45–85 years old with or at risk for knee osteoarthritis. Data included sociodemographics, clinical pain, psychosocial stress, and salivary cortisol across five time points over an approximate 12-hour period. Non-parametric correlation analysis, sociodemographic group comparisons, and regression analyses were performed. Clinical pain and psychosocial stress were associated with salivary cortisol levels, particularly morning waking and the evening to morning awakening slope. With the inclusion of recognized explanatory variables, the Graded Chronic Pain Scale characteristic pain intensity and financial satisfaction were identified as the primary pain and psychosocial measures associated with cortisol levels. Sociodemographic group differences were indicated such that NHB participants reported higher pain-related disability, higher levels of discrimination, lower financial and material satisfaction, and showed higher evening salivary cortisol levels compared to NHW participants. In combined pain and psychosocial stress analyses, greater financial satisfaction, lower pain intensity, and lower depression were associated with higher morning waking saliva cortisol levels while greater financial satisfaction was the only variable associated with greater evening to morning awakening slope. Our findings show relationships among clinical pain, psychosocial stress, sociodemographic factors, and salivary cortisol levels. Importantly, with inclusion of recognized explanatory variables, financial satisfaction remained the primary factor accounting for differences in morning waking cortisol and evening to morning awakening cortisol slope in an ethnic/racially diverse group of middle aged and older adults with or at risk for knee osteoarthritis.