ALPHA-SMOOTH MUSCLE ACTIN, A DIFFERENTIATION MARKER OF SMOOTH-MUSCLE CELLS, IS PRESENT IN MICROFILAMENTOUS BUNDLES OF PERICYTES
ALPHA-SMOOTH MUSCLE ACTIN, A DIFFERENTIATION MARKER OF SMOOTH-MUSCLE CELLS, IS PRESENT IN MICROFILAMENTOUS BUNDLES OF PERICYTES
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DOI：
10.1177/37.3.2918221
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发表时间：
1989-03-01
影响因子：
3.2
通讯作者：
ORCI, L
中科院分区：
文献类型：
--
作者：
SKALLI, O;PELTE, MF;ORCI, L
.alpha。平滑肌肌动蛋白（. α .-sm）是平滑肌细胞（SMC）的一种典型亚型，在血管SMC中大量存在，通过免疫细胞化学在电镜水平上证实了平滑肌肌动蛋白存在于大鼠和人体各种器官的周细胞细胞质中。在SMC和周细胞中，。-sm肌动蛋白定位于微丝束，加强了它是这些细胞类型的功能性同工异构体的假设，并支持周细胞发挥收缩功能的假设。
.alpha.-Smooth muscle (.alpha.-sm) actin, an isoform typical of smooth muscle cells (SMC) and present in high amounts in vascular SMC, was demonstrated in the cytoplasm of pericytes of various rat and human organs by means of immunocytochemistry at the electron microscopic-level. In SMC and pericytes, .alpha.-sm actin was localized in microfilament bundles, strengthening the assumption that it is the functional isoform in these cell types and supporting the assumptions that pericytes exert contractile functions.