Separating practice guidelines from pharmaceutical marketing.
Separating practice guidelines from pharmaceutical marketing.
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将实践指南与药品营销分开。
DOI：
10.1097/01.ccm.0000288106.55246.a5
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发表时间：
2007
影响因子：
8.8
通讯作者：
Danner,RobertL
中科院分区：
文献类型：
--
作者：
Eichacker,PeterQ;Natanson,Charles;Danner,RobertL
我写这封信是为了评论德宾博士在《重症监护医学》（1）中的特别文章。虽然来自工业界的支持对于推进医学会的科学和教育活动以及个人或部门的科学追求是非常宝贵的，但我们必须保持谨慎，因为有时会在无限制支持的字里行间暗示什么。一篇科学或学术文章中的信息似乎受到行业资助的影响是很常见的。制药行业与研究人员和临床医生之间日益增加的财务联系所引起的可信度问题仍在讨论中（2）。我必须承认，当我阅读任何期刊上的一篇文章时，我发现自己不由自主地看着第一页左下角的小字。这是玩世不恭，但我很少找到一篇文章中的信息不支持金融使命的行业支持者。这本身并不一定意味着信息是错误的，但人们是否应该相信一篇文章所拥护的内容，需要对文章进行批判性的分析（包括方法学，如随机化方案、详细的人口统计学资料和受试者的临床特征）;简单地浏览文章或阅读摘要不再足够，在对文章进行批判性分析后，我发现自己不同意摘要中提出的结论，这并不罕见。在移植方面，免疫抑制药物和抗病毒治疗构成了移植后患者护理的一个非常昂贵的方面，我发现该行业的影响也相当普遍，包括科学会议和发表的文章。在行业赞助/支持的科学会议上提出的数据和结论的客观性也受到类似的怀疑（3）。
I am writing to comment on the special article by Dr. Durbin in Critical Care Medicine (1). While support from industry is invaluable in advancing scientific and educational activities of medical societies as well as the scientific pursuits of individuals or departments, we must remain careful of what sometimes is implied to be read between the lines of unrestricted support. A scientific or scholarly article in which the message appears to be influenced by grant support from the industry is quite common. The issue of credibility caused by the increasing financial ties between the pharmaceutical industry and researchers and clinicians continues to be discussed (2). I must admit that when I am reading an article in any journal, I find myself involuntarily looking at the fine print at the lower left corner of the first page. This is cynicism, but I very seldom find an article in which the message does not support the financial mission of the industry supporter. This in itself does not necessarily mean that the message is wrong, but whether one should believe what an article is espousing requires a critical analysis of the article (including the methodology, eg, randomization protocol, detailed demographics, and clinical profiles of the subjects); simply scanning through an article or reading the abstract is no longer sufficient, and not uncommonly I find myself disagreeing with the conclusions projected in the summary abstract after going through a critical analysis of the article. In transplantation, where immunosuppressive medications and antiviral therapy constitute a very expensive aspect of posttransplantation patient care, I find the industry influence quite pervasive also—for scientific meetings as well as published articles. Objectivity of data and conclusions presented in industry-sponsored/supported scientific meetings are also subject to similar skepticism (3).