Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care
Physical illness in patients with severe mental disorders. I. Prevalence, impact of medications and disparities in health care
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DOI：
10.1002/j.2051-5545.2011.tb00014.x
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发表时间：
2011-02-01
期刊：
影响因子：
73.3
通讯作者：
Leucht, Stefan
中科院分区：
文献类型：
--
作者：
De Hert, Marc;Correll, Christoph U.;Leucht, Stefan
与一般人群相比，严重精神疾病（SMI）患者的寿命较短。这种超额死亡率主要是由于身体疾病。我们报告了不同身体疾病的患病率以及重要的个人生活方式选择，精神病治疗的副作用以及导致这些不良身体健康结果的医疗保健获取，利用和提供方面的差异。我们检索了MEDLINE（1966年8月2010年），将精神分裂症、双相情感障碍和重度抑郁症的MeSH术语与一般躯体疾病类别的不同MeSH术语相结合，通过交叉引用选择相关综述和其他相关研究，以确定患病率数据和因素。导致发病率和死亡率过高。营养和代谢疾病，心血管疾病，病毒性疾病，呼吸道疾病，肌肉骨骼疾病，性功能障碍，妊娠并发症，口颌疾病，以及可能与肥胖相关的癌症，与一般人群相比，在SMI患者中更为普遍。此外，有足够的证据表明，重度精神分裂症患者不太可能获得大多数这些疾病的标准护理水平。生活方式因素，相对容易测量，几乎没有考虑筛选;许多重要的物理参数的基线测试进行得不够。除了可改变的生活方式因素和精神药物的副作用外，重度精神病患者获得保健的机会和质量仍有待改善。
The lifespan of people with severe mental illness (SMI) is shorter compared to the general population. This excess mortality is mainly due to physical illness. We report prevalence rates of different physical illnesses as well as important individual lifestyle choices, side effects of psychotropic treatment and disparities in health care access, utilization and provision that contribute to these poor Physical health outcomes. We searched MEDLINE (1966 August 2010) combining the MeSH terms of schizophrenia, bipolar disorder and major depressive disorder with the different MeSH terms of general physical disease categories to select pertinent reviews' and additional relevant studies through cross-referencing to identify prevalence figures and factors. contributing to the excess morbidity and mortality rates. Nutritional and metabolic diseases, cardiovascular diseases, viral diseases, respiratory tract diseases, musculoskeletal diseases, sexual dysfunction, pregnancy complications, stomatognathic diseases, and possibly obesity-related cancers are, compared to the general population, more prevalent among people with SMI It seems that lifestyle as well as treatment specific factors account for much of the increased risk for most of these physical diseases. Moreover, there is sufficient evidence that people with SMI are less likely to receive standard levels of care for most, of these diseases. Lifestyle factors, relatively easy to measure, are barely considered for screening; baseline testing of numerous important physical parameters is insufficiently performed. Besides modifiable lifestyle factors and side effects of psychotropic medications, access to and quality of health care remains to be improved for individuals with SMI.