LONGITUDINAL-STUDIES OF INFECTIOUS-DISEASES AND PHYSICAL GROWTH OF CHILDREN IN RURAL BANGLADESH .2. INCIDENCE OF DIARRHEA AND ASSOCIATION WITH KNOWN PATHOGENS
LONGITUDINAL-STUDIES OF INFECTIOUS-DISEASES AND PHYSICAL GROWTH OF CHILDREN IN RURAL BANGLADESH .2. INCIDENCE OF DIARRHEA AND ASSOCIATION WITH KNOWN PATHOGENS
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DOI：
10.1093/oxfordjournals.aje.a113308
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发表时间：
1982-01-01
影响因子：
5
通讯作者：
HUQ, I
中科院分区：
文献类型：
--
作者：
BLACK, RE;BROWN, KH;HUQ, I
在孟加拉国农村的两个村庄进行了纵向研究，以更多地了解传染病与儿童营养状况之间的相互作用。腹泻疾病，通过监测197名2 - 60个月的儿童确定，在1978 - 1979年研究了细菌、病毒和寄生性肠道病原体。腹泻的年发病率在2 - 11个月的儿童中最高，随着年龄的增长，发病率逐渐下降，从每年每名儿童7次下降到4次。从51%的腹泻期间的直肠培养物和6%的腹泻不存在时的每月培养物中鉴定出肠道病原体。致病菌以大肠埃希菌为主，其次为志贺氏菌和轮状病毒。痢疾相关的腹泻发作持续时间最长;霍乱弧菌或轮状病毒相关的腹泻发作更常与脱水相关。e.大肠杆菌性腹泻在炎热的月份发病率最高;志贺氏菌病在凉爽干燥的月份更常见。
Longitudinal studies were done in 2 villages in rural Bangladesh to learn more about the interactions between infectious diseases and the nutritional status of children. Diarrheal diseases, identified by surveillance of 197 children aged 2-60 mo., were studied for bacterial, viral and parasitic enteropathogens in 1978-1979. The annual incidence of diarrhea was highest in children aged 2-11 mo., and declined progressively with age from 7 to 4 episodes per child per yr. An enteropathogen was identified from rectal cultures taken during diarrhea in 51% of episodes and from 6% of monthly cultures taken when diarrhea was not present. Enterotoxigenic Escherichia coli were the pathogens found most frequently, followed by shigellae and rotaviruses. Diarrheal episodes associated with shigellae had the longest duration; episodes associated with Vibrio cholerae or with rotavirus were more frequently associated with dehydration. E. coli diarrhea had a peak incidence during the hot months; shigellosis was more frequent during the cool, dry months.