INCIDENCE OF ALOPECIA-AREATA IN OLMSTED COUNTY, MINNESOTA, 1975 THROUGH 1989
INCIDENCE OF ALOPECIA-AREATA IN OLMSTED COUNTY, MINNESOTA, 1975 THROUGH 1989
复制标题
DOI：
10.4065/70.7.628
复制
发表时间：
1995-07-01
影响因子：
8.9
通讯作者：
MELTON, LJ
中科院分区：
文献类型：
--
作者：
SAFAVI, KH;MULLER, SA;MELTON, LJ
目的：为了评估社区中脱发患者斑秃（AA）的发病率和自然史，设计：我们对明尼苏达州奥姆斯特德县1975年至1989年的居民进行了一项回顾性的以人群为基础的描述性研究。材料和方法：在15年的研究期间，在确定了292名奥姆斯特德县居民首次被诊断患有AA后，我审查了他们的完整统计分析了不同性别、不同年龄组的影响因素。AA的总体发生率为每100，000人年20.2例，且不随时间而变化。两种性别和所有年龄段的发病率相似，终生风险估计为1.7%。87%的患者仅由皮肤科医生诊断为AA，29%的病例经活检证实，大多数患者的病情为轻度或中度，但21例患者在临床过程中的某个时间点发生了全秃或普秃。这项对社区中AA发病率和自然史的研究表明，这种疾病相当常见，可以在所有年龄段看到，虽然大多数患者预计会自发消退，但一小部分但很大比例的病例（可能约7%）可能会演变为严重和慢性脱发，这可能对受影响的人造成心理社会破坏。
Objective: To assess the incidence and natural history of alopecia areata (AA) among unselected patients from a community.Design: We conducted a retrospective population-based descriptive study of AA among residents of Olmsted County, Minnesota, for the period from 1975 through 1989.Material and Methods: After identifying 292 Olmsted County residents first diagnosed with AA during the 15-year study period, me reviewed their complete (inpatient and outpatient) medical records in the community and statistically analyzed the effects of gender and age-group.Results: The overall incidence of AA was 20.2 per 100,000 person-years and did not change with time. Rates were similar in the two genders and over all ages, and lifetime risk was estimated at 1.7%. Eighty-seven percent of patients mere examined by a dermatologist who diagnosed AA, and 29% of cases were confirmed by biopsy, Most patients had mild or moderate disease, but alopecia totalis or universalis developed at some point during the clinical course in 21 patients.Conclusion: This study of the incidence anti natural history of AA in a community shows that this disorder is fairly common and can be seen at all ages, Although spontaneous resolution is expected in most patients, a small but significant proportion of cases (probably approximately 7%) may evolve into severe and chronic hair loss, which may be psychosocially devastating for affected persons.