Infant birthweight in the US: the role of preconception stressful life events and substance use.
Infant birthweight in the US: the role of preconception stressful life events and substance use.
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婴儿在美国的出生体重：预想的压力性生活事件和用途的作用。
DOI：
10.1007/s00737-015-0595-z
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发表时间：
2016-06
期刊：
影响因子：
--
通讯作者：
Zarak D
中科院分区：
文献类型：
--
作者：
Witt WP;Mandell KC;Wisk LE;Cheng ER;Chatterjee D;Wakeel F;Park H;Zarak D
这项研究的目的是确定怀孕前应激生活事件(PSLEs)、怀孕前和怀孕期间妇女饮酒和烟草使用以及婴儿出生体重之间的关系。数据来自早期儿童纵向研究-出生队列(n=9350)。数据收集于2001年。接触多发性硬化症的定义是父母、配偶或之前出生的孩子死亡、离婚或婚姻分居、或受孕前生育问题的迹象。调查数据确定了怀孕前三个月和怀孕最后三个月期间的烟酒使用量。我们使用阶段性多变量Logistic回归来估计女性使用药物和PSLE对出生体重极低(1,500克)或低(1,500-2,499克)婴儿的风险的影响，调整了混杂因素。与没有经历过任何PSLE的妇女相比，经历过PSLE的妇女更有可能生下极低出生体重的婴儿(调整后的优势比[AOR]：1.35；95%可信区间[CI]：1.10-1.66)。与从不吸烟的妇女相比，在怀孕前(AOR：1.31；95%CI：1.04-1.66)或在最后三个月吸烟(AOR：1.98；95%CI：1.56-2.52)的妇女更有可能生下LBW婴儿。多发性硬化症和妇女在怀孕前和怀孕期间吸烟是生下低出生体重婴儿的独立危险因素。改善生育结果的干预措施可能需要解决妇女在未孕期的健康和健康行为。
The purpose of this study was to determine the relationships among preconception stressful life events (PSLEs), women’s alcohol and tobacco use before and during pregnancy, and infant birthweight. Data were from the Early Childhood Longitudinal Study-Birth Cohort (n=9,350). Data were collected in 2001. Exposure to PSLEs was defined by indications of death of a parent, spouse, or previous live born child; divorce or marital separation; or fertility problems prior to conception. Survey data determined alcohol and tobacco usage during the three months prior to and in the final three months of pregnancy. We used staged multivariable logistic regression to estimate the effects of women’s substance use and PSLEs on the risk of having a very low (<1,500 grams, VLBW) or low (1,500–2,499 grams, LBW) birthweight infant, adjusting for confounders. Women who experienced any PSLE were more likely to give birth to VLBW infants (adjusted odds ratio [AOR]: 1.35; 95% confidence interval [CI]: 1.10–1.66) than women who did not experience any PSLE. Compared to women who never smoked, women who smoked prior to conception (AOR: 1.31; 95% CI: 1.04–1.66) or during their last trimester (AOR: 1.98; 95% CI: 1.56–2.52) were more likely to give birth to LBW infants. PSLEs and women’s tobacco use before and during pregnancy are independent risk factors for having a lower birthweight baby. Interventions to improve birth outcomes may need to address women’s health and health behaviors in the preconception period.
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影响因子：
3.3
作者：
Class QA;Lichtenstein P;Långström N;D'Onofrio BM
通讯作者：
D'Onofrio BM
影响因子：
4.7
作者：
HOLMES, TH;RAHE, RH
通讯作者：
RAHE, RH
影响因子：
3.3
作者：
Khashan, Ali S.;McNamee, Roseanne;Baker, Philip N.
通讯作者：
Baker, Philip N.
影响因子：
4.2
作者：
Lobel, Marci;Cannella, Dolores Lacey;Meyer, Bruce A.
通讯作者：
Meyer, Bruce A.
影响因子：
5.5
作者：
Pirie, PL;Lando, H;Grothaus, LC
通讯作者：
Grothaus, LC