Recent structural insights into the enzymology of the ubiquitous plant cell wall glycan xyloglucan

Recent structural insights into the enzymology of the ubiquitous plant cell wall glycan xyloglucan
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DOI:
10.1016/j.sbi.2016.07.005
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发表时间:
2016-10-01
影响因子:
6.8
通讯作者:
Brumer, Harry
Brumer, Harry
中科院分区:
生物学2区
文献类型:
--
作者:
Attia, Mohamed A.;Brumer, Harry

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木葡聚糖(XyGs)构成高度修饰的β(1 -> 4)-葡聚糖家族,其成员在植物界中广泛且丰富。因此,XyG构成了多种植物病原微生物、腐殖微生物和肠道共生微生物的代谢可及单糖的重要储备。为了克服XyG中不同糖苷键的内在稳定性,细菌和真菌已经进化出来自多个家族的广泛的木葡聚糖活性酶库,其精细适应的三级结构最近被曝光。
The xyloglucans (XyGs) constitute a family of highly decorated beta(1 -> 4)-glucans whose members are widespread and abundant across the plant kingdom. As such, XyGs constitute a significant reserve of metabolically accessible monosaccharides for diverse phytopathogenic, saprophytic, and gut symbiotic micro-organisms. To overcome the intrinsic stability of the diverse glycosidic bonds in XyGs, bacteria and fungi have evolved extensive repertoires of xyloglucan-active enzymes from manifold families, whose exquisitely adapted tertiary structures are recently coming to light.