Comorbidity of depression with chronic diseases: A population-based study in Aleppo, Syria
Comorbidity of depression with chronic diseases: A population-based study in Aleppo, Syria
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DOI：
10.2190/pm.38.2.d
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发表时间：
2008-01-01
影响因子：
2
通讯作者：
Ward, Kenneth D.
中科院分区：
文献类型：
--
作者：
Kilzieh, Nael;Rastam, Samar;Ward, Kenneth D.
目的：评估叙利亚阿勒颇社区慢性病患者抑郁症的共患病率及其相关因素。这在以前从未在阿拉伯国家进行过调查。方法：我们在阿勒颇对18-65岁的成年人（N = 2038）进行了一项横断面、基于人群的研究。我们使用结构化视图间问卷收集数据。社会人口统计学，一般健康信息，和医生诊断的抑郁症和慢性疾病的自我报告，在过去的一年中活跃。我们使用逻辑回归来估计慢性疾病中抑郁症的几率以及抑郁症与慢性疾病共病的社会人口统计学相关性。结果：平均年龄（SD）为35.3（12.1）岁，55%为女性。在女性中，抑郁症的预测因子是心脏病（OR = 3.95，95%CI：1.50-10.40）、高血压（OR = 2.92，95%CI：1.53-5.55）和肾脏疾病（OR = 2.96，95%CI：1.64-5.32）。抑郁症与任何慢性疾病的共病率随着社会经济地位的提高而降低（中与低：OR = 0.28，95%CI：0.12-0.65;高与低：OR = 0.20，95%CI：0.05-0.81）。在男性中，抑郁症的预测因子是风湿病（OR = 7.10，95%CI：2.58-19.60）和呼吸系统疾病（OR = 3.77，95%CI：1.23-11.60）。居住在正式区的抑郁共患病率降低（OR = 0.22，95%CI：0.06-0.80）。结论：抑郁症与阿勒颇社区的许多慢性病有关，这一发现与其他文化的报告一致。确定了与性别有关的潜在风险因素。调查结果为公共心理健康规划提供了信息，并支持在初级保健环境中提供抑郁症治疗。
Objective: To assess the comorbidity and correlates of depression in chronic diseases in the community in Aleppo, Syria. This has never been previously investigated in an Arab country. Method: We conducted a cross-sectional, population-based study in Aleppo on adults aged 18-65 (N = 2038). We collected data utilizing a structured inter-view questionnaire. Socio-demographics, general health information, and self-report of physician-diagnosed depression and chronic diseases active in the past year were obtained. We used logistic regression to estimate the odds of depression in chronic diseases and socio-demographic correlates of depression comorbid with chronic diseases. Results: Mean age (SD) was 35.3 (12.1) years, 55% were female. In women, predictors of depression were heart disease (OR = 3.95, 95% CI: 1.50-10.40), hypertension (OR = 2.92, 95% CI: 1.53-5.55), and kidney disease (OR = 2.96, 95% Cl: 1.64-5.32). Depression comorbidity with any chronic disease decreased in higher socio-economic status (middle vs. low: OR = 0.28, 95% CI: 0.12-0.65; high vs. low: OR = 0.20, 95% CI: 0.05-0.81). In men, predictors of depression were rheumatism (OR = 7.10, 95% CI: 2.58-19.60) and respiratory disease (OR = 3.77, 95% CI: 1.23-11.60). Depression comorbidity decreased in residence in formal zones (OR = 0.22, 95% CI: 0.06-0.80). Conclusion: Depression is associated with many chronic diseases in the community in Aleppo, a finding consistent with reports from other cultures., Potential gender-related risk factors were identified. Findings inform public mental health planning and support the delivery of depression treatment in primary care settings.