Synthesis of the C(1)-C(25) fragment of amphidinol 3: Application of the double-allylboration reaction for synthesis of 1,5-diols
Synthesis of the C(1)-C(25) fragment of amphidinol 3: Application of the double-allylboration reaction for synthesis of 1,5-diols
复制标题
DOI：
10.1021/ol050250q
复制
发表时间：
2005-03-31
期刊：
影响因子：
5.2
通讯作者：
Roush, WR
中科院分区：
文献类型：
--
作者：
Flamme, EM;Roush, WR
本文报道了安地醇3的C（1）-C（25）片段的合成。该合成的特征在于双烯丙基硼化反应方法的两个应用，用于高度立体选择性地合成C（1）-C（15）链段中的1，5-二醇单元。
A synthesis of the C(1)-C(25) fragment of amphidinol 3 is described. The synthesis features two applications of double allylboration reaction methodology for the highly stereoselective synthesis of 1,5-diol units in the C(l)-C(15) segment.