Viral assembly: a molecular modeling perspective.
Viral assembly: a molecular modeling perspective.
复制标题
病毒组装：分子建模视角。
DOI：
10.1039/b912884k
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Boz,MustafaBurak
中科院分区：
文献类型：
--
作者：
Harvey,StephenC;Petrov,AntonS;Devkota,Batsal;Boz,MustafaBurak
Icosahedral viruses are among the smallest and simplest of biological systems. The investigation of their structures represented the first step toward the establishment of molecular biophysics, over half a century ago. Many research groups are now pursuing investigations of viral assembly, a process that could offer new opportunities for the design of antiviral drugs and novel nanoparticles. A variety of experimental, theoretical and computational methods have been brought to bear on the study of virus structure and assembly. In this Perspective we review the contributions of theoretical and computational approaches to our understanding of the structure, energetics, thermodynamics and assembly of DNA bacteriophage and single-stranded icosahedral RNA viruses.
