Ethanol oxidation by intestinal microsomes: increased activity after chronic ethanol administration.
Ethanol oxidation by intestinal microsomes: increased activity after chronic ethanol administration.
复制标题
肠道微粒体的乙醇氧化：长期施用乙醇后活性增加。
DOI：
10.1016/0024-3205(79)90422-3
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发表时间：
1979
期刊：
影响因子：
6.1
通讯作者：
Charles S. Lieber
中科院分区：
文献类型：
--
作者：
Helmut K. Seitz;Helmut K. Seitz;M. Korsten;M. Korsten;Charles S. Lieber;Charles S. Lieber
在大鼠中，慢性乙醇摄入增加近端小肠粘膜细胞的微粒体蛋白，提高细胞色素P-450含量和NADPH细胞色素-C-还原酶活性。肠道氧化乙醇微粒体系统被证明，以及其增强后，慢性乙醇管理。
In the rat, chronic ethanol ingestion increases microsomal protein of the mucosal cells of the proximal small intestine, enhances cytochrome P-450 content and NADPH cytochrome-C-reductase activity. Intestinal oxidation of ethanol by a microsomal system is demonstrated as well as its enhancement after chronic ethanol administration.