Forward-viewing photoacoustic imaging probe with bundled ultra-thin hollow optical fibers
Forward-viewing photoacoustic imaging probe with bundled ultra-thin hollow optical fibers
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DOI：
10.1088/2040-8978/18/7/074015
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发表时间：
2016-06
影响因子：
2.1
通讯作者：
A. Seki;K. Iwai;T. Katagiri;Y. Matsuura
中科院分区：
文献类型：
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作者：
A. Seki;K. Iwai;T. Katagiri;Y. Matsuura
提出了一种用于内窥镜诊断的光声成像系统。在该系统中，制作了一束127根内径为100 μm的中空光纤。束的总直径为2.1 mm，最小弯曲半径约为10 mm。由于空心光纤的数值孔径小，无需在远端使用透镜阵列即可获得高分辨率图像。在成像系统中，束中的中空纤维在输入端排列，因此在输入端对激光束进行线性扫描，从而依次激发中空纤维。建立了由用于声波激发的束状光纤和光声信号探测的压电探针组成的光声成像系统。利用该系统对鱼类卵巢膜血管进行了光声成像，验证了该系统的可行性。结果，在约6.6 mJ cm−2的激光影响下，成功地获得了血管的光声图像。
A photoacoustic imaging system composed of a flexible bundle of thin hollow-optical fibers is proposed for endoscopic diagnosis. In this system, a bundle of 127 hollow-optical fibers with an inner diameter of 100 μm was fabricated. The total diameter of the bundle was 2.1 mm, and the minimum bending radius was around 10 mm. Owing to the small numerical aperture of hollow optical fibers, a high resolution image was obtained without using a lens array at the distal end. In the imaging system, the hollow fibers in the bundle were aligned at the input end, so the hollow fibers were sequentially excited by linearly scanning the laser beam at the input end. Photoacoustic imaging systems consisting of the bundled fibers for excitation of acoustic wave and piezoelectric probes for detection of photoacoustic signals were built. By using the systems, photoacoustic images of blood vessels in the ovarian membrane of fish were taken to test the feasibility of the system. As a result, photoacoustic images of the vessel were successfully obtained with a laser fluence of around 6.6 mJ cm−2.