Central interaction between the baroreceptor reflexes from the carotid sinus and aortic arch.
Central interaction between the baroreceptor reflexes from the carotid sinus and aortic arch.
复制标题
来自颈动脉窦和主动脉弓的压力感受器反射之间的中枢相互作用。
DOI：
--
复制
发表时间：
1979
影响因子：
--
通讯作者：
P. Lalley
中科院分区：
文献类型：
--
作者：
J. Kendrick;G. Matson;P. Lalley
在吗啡-氯醛糖麻醉下，观察了电刺激主动脉神经（AN）和颈动脉窦神经（CSN）的心血管反应。同侧两种神经的联合刺激导致全身动脉降压反应和心脏减慢，分别比单独刺激这些神经的反应之和高59%和77%（P <0.05）。对侧联合刺激这些神经的降压反应与单独刺激的反应之和没有差异（P> 0.05）。然而，对侧神经刺激的心脏减慢仍然比个体反应的总和高43%（P <0.05）。结果表明，主动脉和颈动脉压力感受性反射之间的相互作用发生在中央，这会导致一个更大的自主输出的加性效应。反射之间的相互作用的程度没有改变的刺激列车之间的延迟是变化的间隔为0和100毫秒。在间隔大于100毫秒的反射反应是添加剂。
The cardiovascular response to combined stimulation of the aortic nerve (AN) and carotid sinus nerve (CSN) with trains of electrical stimuli was studied in dogs under morphine-chloralose anesthesia. Combined stimulation of both nerves ipsilaterally resulted in systemic arterial depressor responses and cardiac slowing that were 59% and 77% greater (P less than 0.05) than the respective sum of the responses to separate stimulation of these nerves. The depressor response to combined stimulation of these nerves contralaterally was not different (P greater than 0.05) from the sum of the separate responses. However, cardiac slowing to contralateral stimulation of the nerves remained 43% greater (P less than 0.05) than the sum of the individual responses. The results suggest that an interaction between the aortic and carotid baroreceptor reflexes occurs centrally, which causes a greater than additive effect on the autonomic output. The degree of interaction between the reflexes did not change as the delay between the stimulus trains was varied over an interval of 0 and 100 ms. At intervals greater than 100 ms the reflex responses were additive.