Prevalence and severity of asthma and allergies in schoolchildren in Lhasa, Tibet
Prevalence and severity of asthma and allergies in schoolchildren in Lhasa, Tibet
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DOI：
10.1111/j.1365-2222.2007.02781.x
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发表时间：
2007-09-01
影响因子：
6.1
通讯作者：
Song, P.
中科院分区：
文献类型：
--
作者：
Droma, Y.;Kunii, O.;Song, P.
背景：国际儿童哮喘和过敏症研究(ISAAC)表明，哮喘、过敏性鼻结膜炎和湿疹在世界各地的患病率存在很大差异，环境因素和生活习惯是这些疾病患病率和严重程度的主要决定因素。目的在海拔3658m的藏族自治区拉萨市开展艾萨克三期项目，调查13~14岁儿童哮喘、过敏性鼻结膜炎和湿疹的发病情况。方法对拉萨市城区8所公立初中3 196名13~14岁儿童进行书面和视频问卷调查。结果在总体观察中，“有过喘息”、“现在有喘息”和“诊断为哮喘”的患病率分别为1.4%、0.8%和1.1%。目前运动性哮喘和夜间咳嗽的患病率分别为7.1%和4.6%。目前过敏性鼻结膜炎和湿疹的患病率分别为5.2%和0.4%。此外，过去12个月鼻结膜炎症状的患病率在全年没有明显差异。结论过去12个月哮喘、过敏性鼻结膜炎和湿疹的患病率是全球实施艾萨克的中心中最低的。
Background The International Study of Asthma and Allergies in Childhood (ISAAC) demonstrated that large variations existed in the prevalence of symptoms of asthma, allergic rhinoconjunctivitis and eczema throughout the world and that environmental factors and lifestyle customs are major determinants of the prevalence and severity of these diseases. However, the relevant data about children living at high-altitude locations were considered to be underreported.Objective The ISAAC Phase III programme was carried out in Lhasa, the Tibetan Autonomous Region in China, at an elevation of 3658 m above sea level to examine the occurrence of asthma, allergic rhinoconjunctivitis and eczema in schoolchildren aged 13-14 years.Methods All 3196 schoolchildren in eight public junior high schools in urban Lhasa who were confirmed to be 13-14 years old were invited and participated in both written and video questionnaire investigations, among which 3190 pieces of data (49.8% of boys and 50.2% of girls) were validated and analysed.Results Among the overall observations, the prevalence of 'having ever experienced wheezing', 'current wheezing' and 'diagnosed to have asthma' was 1.4%, 0.8% and 1.1%, respectively. The prevalence of current exercise-induced asthma and current nocturnal cough was 7.1% and 4.6%, respectively. The current prevalence of allergic rhinoconjunctivitis and eczema was 5.2% and 0.4%, respectively. In addition, the prevalence of rhinoconjunctivitis symptoms during the past 12 months showed no discernable differences throughout the year.Conclusion The prevalence of asthma, allergic rhinoconjunctivitis and eczema over the past 12 months was the lowest among the centres, that performed ISAAC worldwide.