An outbreak of Burkholderia multivorans beyond cystic fibrosis patients

An outbreak of Burkholderia multivorans beyond cystic fibrosis patients
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DOI:
10.1016/j.jhin.2013.04.001
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发表时间:
2013-07-01
影响因子:
6.9
通讯作者:
Kolar, M.
Kolar, M.
中科院分区:
医学3区
文献类型:
--
作者:
Hanulik, V.;Webber, M. A.;Kolar, M.

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洋葱伯克霍尔德氏菌复合体(BCC)菌株是一种条件致病菌,能够在囊性纤维化患者中引起严重感染。最近,我们在奥洛穆克大学医院发现了一起疑似BCC感染暴发。从52例患者中分离出74株BCC菌株,其中大多数(N=48)没有囊性纤维化。最常见的是多食伯克霍尔德氏菌(N=46),其中24株(52.2%)为克隆株。其中15株是从重症监护患者中分离出来的,其中5人死于医院获得性肺炎。B.多食性病毒可导致囊性纤维化患者以外的严重感染暴发。(C)2013年医疗感染学会。爱思唯尔有限公司出版。保留所有权利。
Strains of the Burkholderia cepacia complex (Bcc) are opportunistic pathogens capable of causing serious infection in cystic fibrosis patients. Recently we identified a suspected outbreak of infection with Bcc strains at the University Hospital Olomouc. Seventy-four Bcc strains were isolated from 52 patients, most of whom (N = 48) did not suffer from cystic fibrosis. Most frequently (N = 46) Burkholderia multivorans was isolated and 24 (52.2%) of these strains were clonal. Fifteen of these strains were isolated from intensive care patients, five of whom died from hospital-acquired pneumonia. B. multivorans can cause serious outbreaks of infection beyond cystic fibrosis sufferers. (C) 2013 The Healthcare Infection Society. Published by Elsevier Ltd. All rights reserved.