Metastatic breast cancer to the gastrointestinal tract: report of five cases and review of the literature.
Metastatic breast cancer to the gastrointestinal tract: report of five cases and review of the literature.
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DOI：
10.1155/2012/439023
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发表时间：
2012
影响因子：
1.9
通讯作者：
Cavanna L
中科院分区：
文献类型：
--
作者：
Ambroggi M;Stroppa EM;Mordenti P;Biasini C;Zangrandi A;Michieletti E;Belloni E;Cavanna L
乳腺癌的腔内胃肠道（GI）转移是罕见的，报道是不完整和贫乏的。本研究的目的是通过一项单一机构的回顾性研究来评估乳腺癌对胃肠道的影响，并复习相关文献。在2007年1月至2011年12月期间，共有980例乳腺癌患者在我院接受治疗，对患者记录和报告数据库进行分析。本研究获得了机构审查委员会的批准。使用PubMed、CancerLit、Embase进行文献检索。本综述选取2012年6月前发表的英文论文。980例乳腺癌患者中5例（0.5%）出现胃肠道转移，3例累及胃，1例累及空肠，1例累及直肠。回顾文献，我们确定了206例乳腺癌胃肠道转移患者：最常见的转移部位是胃（60%）。多数患者接受了化疗和内分泌治疗，部分患者接受了手术和放疗。乳腺癌的胃肠道转移是罕见的，但也是可能的，而且很晚也会发生复发。细胞组织学诊断是必须的，以区分胃肠道转移从乳腺癌到其他疾病，并允许适当的治疗。
Luminal gastrointestinal (GI) metastases from breast cancer are rare, reports are fragmentary and poor. The purposes of this study are to assess the gastrointestinal involvement from breast cancer in a retrospective study at a single institution and reviewing the related literature. Between January 2007 and December 2011 a total of 980 patients with breast cancer were treated at our institution, patients' records and report database were analysed. Institutional Review Board approval was obtained for this study. A search of the literature using PubMed, CancerLit, Embase, was performed. Selected for the present review were papers published in English before June 2012. Five of 980 patients (0.5%) showed gastrointestinal metastases from breast cancer, 3 patients had gastric involvement, 1 jejunum, and 1 rectum. Reviewing the literature, 206 patients affected by gastrointestinal metastasis from breast cancer were identified: the most frequent site of metastasis was the stomach (60%). The majority of the patients underwent chemotherapy and endocrine therapy, someone surgery and radiotherapy. GI metastases from breast cancer are rare, but possible, and a very late recurrence can also occur. Cyto-histological diagnosis is mandatory, to differentiate GI metastases from breast cancer to other diseases and to allow an adequate treatment.