Chest Dynamic-Ventilatory Digital Radiography in Chronic Obstructive or Restrictive Lung Disease.
Chest Dynamic-Ventilatory Digital Radiography in Chronic Obstructive or Restrictive Lung Disease.
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DOI：
10.2147/copd.s309960
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发表时间：
2021
影响因子：
2.8
通讯作者：
Kasahara K
中科院分区：
文献类型：
--
作者：
Ohkura N;Tanaka R;Watanabe S;Hara J;Abo M;Nakade Y;Horii J;Matsuura Y;Inoue D;Takata M;Tamura M;Matsumoto I;Sanada S;Kasahara K
本研究的目的是确定从动态澄清数字X线摄影（DR）和澄清障碍获得的参数之间的关系。这项研究包括273名患有呼吸系统疾病的参与者，他们接受了肺功能测定和功能残气量测量（104例肺功能正常者作为对照，139例阻塞性肺病，30例限制性肺疾病）进行了动态评估-通过动态平板摄影机以每秒15帧的速度拍摄患者缓慢和最大呼吸的连续胸部X线摄影图像，平板成像系统系统测量以下参数：最大吸气时的肺面积除以高度（肺面积_in/高度）、呼吸运动引起的气管直径变化、气管狭窄率、呼吸运动和呼吸运动引起的肺面积变化率。分析了这些参数与功能障碍之间的关系。限制性障碍患者的肺面积/高度显著降低。与对照组和限制性障碍患者相比，阻塞性疾病患者的气管直径变化和气管狭窄率显著增加。阻塞性疾病和限制性疾病患者的运动和肺面积变化率降低。以限制性疾病为参照，肺面积/身高的曲线下面积（AUC）、敏感性和特异性分别为0.88、0.77和0.88。以阻塞性疾病为参照，气管狭窄率的AUC、灵敏度和特异度分别为0.67、0.53和0.81。动态增强DR显示出作为检测和评价呼吸系统疾病患者增强障碍的方法的潜力。
The aim of this study was to identify the relationships between parameters obtained from dynamic-ventilatory digital radiography (DR) and ventilatory disorders. This study comprised 273 participants with respiratory diseases who underwent spirometry and functional residual capacity measurements (104 with normal findings on spirometry as controls, 139 with an obstructive lung disorder, 30 with a restrictive lung disorder) were assessed by dynamic-ventilatory DR. Sequential chest radiography images of the patient’s slow and maximum breathing were captured at 15 frames per second by a dynamic flat-panel imaging system. The system measured the following parameters: lung area at maximum inspiration divided by height (lung area_in/height), changes in tracheal diameter due to respiratory motions, rate of tracheal narrowing, diaphragmatic motion, and rate of change in lung area due to respiratory motion. Relationships between these parameters and ventilatory disorders were analyzed. Lung area_in/height in patients with restrictive disorders showed significant decreases. Tracheal diameter change and tracheal narrowing rate in patients with obstructive disorders were significantly increased compared to both the control participants and patients with restrictive disorders. Patients with obstructive disorders and patients with restrictive disorders showed decreased diaphragmatic motion and lung area change rate. With the restrictive disorders as references, the area under the curve (AUC), sensitivity and specificity of lung area_in/height were 0.88, 0.77, and 0.88, respectively. With the obstructive disorders as references, the AUC, sensitivity and specificity of tracheal narrowing rate were 0.67, 0.53 and 0.81, respectively. Dynamic-ventilatory DR shows potential as a method for the detection and evaluation of ventilatory disorders in patients with respiratory diseases.