Concise Reviews: Cancer Stem Cell Targeted Therapies: Toward Clinical Success.
Concise Reviews: Cancer Stem Cell Targeted Therapies: Toward Clinical Success.
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DOI:
10.1002/sctm.18-0123
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发表时间:
2019-01
影响因子:
6
通讯作者:
Gerson SL
中科院分区:
文献类型:
--
作者:
Desai A;Yan Y;Gerson SL
Cancer stem cells (CSCs) are a subpopulation of cells within tumors that possess the stem cell characteristics of self‐renewal, quiescence, differentiation, and the ability to recapitulate the parental tumor when transplanted into a host. CSCs are correlated with poor clinical outcome due to their contribution to chemotherapy resistance and metastasis. Multiple cell surface and enzymatic markers have been characterized to identify CSCs within a heterogeneous tumor, and here we summarize ongoing preclinical and clinical efforts to therapeutically target these cells and improve patient outcomes. Stem Cells Translational Medicine 2019;8:75–81
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影响因子:
4
作者:
Chen HC;Joalland N;Bridgeman JS;Alchami FS;Jarry U;Khan MWA;Piggott L;Shanneik Y;Li J;Herold MJ;Herrmann T;Price DA;Gallimore AM;Clarkson RW;Scotet E;Moser B;Eberl M
通讯作者:
Eberl M
DOI:
10.1016/j.bbrc.2014.03.047
发表时间:
2014-04-18
影响因子:
3.1
作者:
Duan, Lincan;Shen, Hongmei;Huang, Yunchao
通讯作者:
Huang, Yunchao
影响因子:
11.4
作者:
Busfield, S. J.;Biondo, M.;Nash, A. D.
通讯作者:
Nash, A. D.
影响因子:
4.4
作者:
Castriconi, Roberta;Daga, Antonio;Bottino, Cristina
通讯作者:
Bottino, Cristina
影响因子:
20.3
作者:
Al-Hussaini, Muneera;Rettig, Michael P.;DiPersio, John F.
通讯作者:
DiPersio, John F.