Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer
Complete or near-complete nucleotide sequences of hepatitis E virus genome recovered from a wild boar, a deer, and four patients who ate the deer
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DOI：
10.1016/j.virol.2004.10.006
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发表时间：
2004-12-20
期刊：
影响因子：
3.7
通讯作者：
Mishiro, S
中科院分区：
文献类型：
--
作者：
Takahashi, K;Kitajima, N;Mishiro, S
人畜共患病与戊型肝炎病毒（HEV）传播有关。我们检查了生活在日本兵库县森林中的野猪，在7只野猪中的3只中发现了HEV RNA。来自其中一个的全基因组HEV分离株与以前在同一森林中狩猎的野鹿分离株以及四名吃了生肉后感染戊型肝炎的患者的分离株有99.7%相同。这些研究结果表明，在野猪和鹿的野生生活中存在种间HEV传播，并且这两种动物都可能作为人类的感染源。(C)2004年爱思唯尔公司All rights reserved.
Zoonosis has been implicated in hepatitis E virus (HEV) transmission. We examined wild boar living in a forest of Hyogo prefecture, Japan, and found HEV RNA in three of seven boars. A full-genome HEV isolate from one of them was revealed to be 99.7% identical to a previous isolate from a wild deer hunted in the same forest and to those from four patients who contracted hepatitis E after eating raw meat of the deer. These findings suggest an interspecies HEV transmission between boar and deer in their wild life, and that both animals might serve as an infection source for human beings as suggested previously. (C) 2004 Elsevier Inc. All rights reserved.