Hedonics of taste influence the gastric emptying in rats
Hedonics of taste influence the gastric emptying in rats
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DOI：
10.1016/j.physbeh.2009.01.013
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发表时间：
2009-03-23
影响因子：
2.9
通讯作者：
Yamamoto, Takashi
中科院分区：
文献类型：
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作者：
Inui-Yamamoto, Chizuko;Furudono, Yuichi;Yamamoto, Takashi
众所周知，味觉在包括食欲、营养选择、食物摄入和消化的各种功能中起重要作用。为了研究味觉刺激对消化功能的调节作用，我们用Wistar雄性大鼠测定了具有食欲和厌恶性味道的实验食物的胃排空。将大鼠随机分为3组：每组训练每天进食由粉状食物（4 g）和溶液（4 g）组成的糊状混合物（8 g）30 min。溶液是蒸馏水、糖精溶液作为可口的味道，或奎宁溶液作为厌恶的味道。在试验当天，测量每只大鼠胃内容物的前和30，150。或开始食用麦芽浆后300分钟。结果表明，与未掺杂的麦芽浆相比，食用后150 min，适口麦芽浆使胃的食物输出量增加，而厌恶麦芽浆使胃的食物输出量减少。有没有显着差异，在3组之间的胃排空后的两个外周味神经分支，鼓索和舌咽神经，或胃内灌注后的每一个麦芽汁。在建立了对糖精的条件性味觉厌恶之后，糖精醪在增加胃排空方面变得无效。这些结果表明，快乐积极的口味增加，但快乐消极的口味减少胃排空方面的胃功能。(C)2009 Elsevier Inc. All rights reserved.
It is known that taste sensation plays important roles in various functions including appetite, nutriental choices, food intake and digestion. To study the modulation of digestive functions by taste stimulation, we measured the gastric emptying of experimental foods with appetitive or aversive tastes in Wistar male rats. Rats were randomly divided into 3 groups: each group was trained to eat a mash mixture (8 g) made up with powdered food (4 g) and a solution (4 g) for 30 min per day. The solution was either distilled water, saccharin solution as a palatable taste, or quinine solution as an aversive taste. On the test day, the contents of the stomach of each rat were measured before and 30, 150. or 300 min after the start of eating the mash. The results showed that the food output from the stomach was increased by the palatable mash and was decreased by the aversive mash in comparison with non-adulterated mash 150 min after eating. There were no significant differences in gastric emptying among the 3 groups after deafferentation of the two peripheral taste nerve branches, the chorda tympani and glossopharyngeal nerves, or after intragastric infusions of each mash. After the establishment of conditioned taste aversions to saccharin, saccharin mash became ineffective in increasing gastric emptying. These results show that hedonically positive tastes increase, but hedonically negative tastes decrease gastric function in terms of gastric emptying. (C) 2009 Elsevier Inc. All rights reserved.