Multisensory activation of the intraparietal area when classifying grating orientation: A functional magnetic resonance imaging study
Multisensory activation of the intraparietal area when classifying grating orientation: A functional magnetic resonance imaging study
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DOI：
10.1523/jneurosci.0822-06.2006
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发表时间：
2006-07-12
影响因子：
5.3
通讯作者：
Lederman, Susan J.
中科院分区：
文献类型：
--
作者：
Kitada, Ryo;Kito, Tomonori;Lederman, Susan J.
人类可以通过触摸判断光栅方向。先前的研究表明，纹外皮层参与触觉方向判断，表明该区域与视觉意象相关。然而，目前尚不清楚哪种神经机制对于方向的触觉处理至关重要，因为触觉空间任务并不总是需要视觉图像。我们期望这种神经机制涉及多感觉区域，因为我们对空间的感知是跨模式高度整合的。目前的研究在光栅方向分类过程中使用功能磁共振成像来评估负责方向多感官空间处理的神经基质。我们假设，无论感觉方式如何，顶内沟（IPS）内的一个区域都将参与定向处理。十六名人类受试者对被动触摸的光栅的方向进行了分类，并用右手和左手执行了两项控制任务。与相同刺激的粗糙度分类相比，无论使用哪只手，触觉方向分类都会激活右侧中央后沟和 IPS 周围的区域。通过评估双手触觉空间处理的半球效应，证实了这些区域的右侧激活。相反，与相同刺激的颜色分类相比，视觉方向分类激活了左枕中回。此外，视觉定向分类激活了右侧 IPS 的一部分，该部分也被触觉定向任务激活。因此，我们建议右侧 IPS 的一部分参与光栅方向的多感官空间处理。
Humans can judge grating orientation by touch. Previous studies indicate that the extrastriate cortex is involved in tactile orientation judgments, suggesting that this area is related to visual imagery. However, it has been unclear which neural mechanisms are crucial for the tactile processing of orientation, because visual imagery is not always required for tactile spatial tasks. We expect that such neural mechanisms involve multisensory areas, because our perception of space is highly integrated across modalities. The current study uses functional magnetic resonance imaging during the classification of grating orientations to evaluate the neural substrates responsible for the multisensory spatial processing of orientation. We hypothesized that a region within the intraparietal sulcus (IPS) would be engaged in orientation processing, regardless of the sensory modality. Sixteen human subjects classified the orientations of passively touched gratings and performed two control tasks with both the right and left hands. Tactile orientation classification activated regions around the right postcentral sulcus and IPS, regardless of the hand used, when contrasted with roughness classification of the same stimuli. Right-lateralized activation was confirmed in these regions by evaluating the hemispheric effects of tactile spatial processing with both hands. In contrast, visual orientation classification activated the left middle occipital gyrus when contrasted with color classification of the same stimuli. Furthermore, visual orientation classification activated a part of the right IPS that was also activated by the tactile orientation task. Thus, we suggest that a part of the right IPS is engaged in the multisensory spatial processing of grating orientation.