A 2.5-year follow-up of depression, life crises, and treatment effects on abstinence among opioid addicts.
A 2.5-year follow-up of depression, life crises, and treatment effects on abstinence among opioid addicts.
复制标题
DOI：
10.1001/archpsyc.1986.01800080019003
复制
发表时间：
1986-08
影响因子：
--
通讯作者：
T. Kosten;B. Rounsaville;H. Kleber
中科院分区：
文献类型：
--
作者：
T. Kosten;B. Rounsaville;H. Kleber
后续研究表明，治疗增加了成瘾者保持戒断的可能性，抑郁症和生活危机与戒断率下降有关。一个重要的问题是，接受治疗在多大程度上可以减轻生活危机和抑郁等心理社会风险因素，并减少前吸毒成瘾者继续滥用药物的脆弱性。在我们对268名阿片类药物成瘾者进行的为期2.5年的随访中，药物滥用治疗通常与戒断率增加相关，生活危机和抑郁是持续药物滥用的重要危险因素。然而，这些风险因素的影响通过药物滥用治疗得到改善。虽然生活危机比抑郁症的影响更大，但这两个风险因素在增加继续滥用药物的风险方面具有叠加效应。在生活危机的类型中，争论和损失（“退出”）与抑郁症作为药物滥用的预测因子具有非常强的累加效应。
Follow-up studies have suggested that treatment increases addicts' likelihood of remaining abstinent and that depression and life crises are associated with decreased abstinence. An important issue is to what extent receiving treatment can ameliorate psychosocial risk factors such as life crises and depression and decrease ex-addicts' vulnerability to continued drug abuse. In our 2.5-year follow-up of 268 opiate addicts, drug abuse treatment was generally associated with increased abstinence, and life crises and depression were significant risk factors for continued drug abuse. The impact of these risk factors, however, was ameliorated by drug abuse treatment. Although life crises had a greater impact than depression, these two risk factors had additive effects in increasing the risk for continued drug abuse. Among the types of life crises, arguments and losses ("exits") had very strong additive effects with depression as predictors of drug abuse.