Comparison of dynamic contour tonometry with Goldmann applanation tonometry
Comparison of dynamic contour tonometry with Goldmann applanation tonometry
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DOI：
10.1167/iovs.04-0018
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发表时间：
2004-09-01
影响因子：
4.4
通讯作者：
Thiel, MA
中科院分区：
文献类型：
--
作者：
Kaufmann, C;Bachmann, LM;Thiel, MA
目的.动态轮廓眼压计（DCT; Pascal tonometer）是一种设计用于测量眼内压（IOP）的新型眼压计，与角膜特性无关。本研究的目的是比较DCT与Goldmann压平眼压计（GAT）的IOP读数的平均值，眼结构因素对IOP读数的影响，以及观察者内和观察者间的变异性，在一个大的健康受试者组。在一项228只眼的前瞻性研究中，比较了GAT和DCT测量的IOP，并分析了中央角膜厚度（CCT）、角膜曲率、眼轴长度和前房深度的影响。为了评估观察者内和观察者间的变异性，通过四个眼内压计测量了8只眼睛的IOP。DCT和GAT获得的IOP读数之间具有高度一致性。然而，DCT组的IOP读数始终高于GAT组（中位差异：+ 1.7 mm Hg，四分位距[第25 - 75百分位数] = 0.8 - 2.7 mm Hg）。与GAT相比，多变量回归分析显示角膜厚度、角膜曲率、散光、前房深度和眼轴长度对DCT读数无显著影响。对于重复测量，DCT的观察者内变异性为0.65 mm Hg，GAT的观察者内变异性为1.1 mm Hg（P = 0.008）。DCT和GAT的观察者间变异性分别为0.44 mm Hg和1.28 mm Hg（P = 0.017）。通过DCT测量的IOP与从GAT获得的IOP读数高度一致，但CCT没有变化，并且观察者内和观察者间的变异性较低。DCT似乎是一个适当的方法，眼压常规临床使用。
PURPOSE. The dynamic contour tonometer (DCT; Pascal tonometer) is a novel tonometer designed to measure intraocular pressure (IOP) independent of corneal properties. The purpose of this study was a comparison of the DCT with the Goldmann applanation tonometer ( GAT) with respect to mean of IOP readings, the influence of ocular structural factors on IOP readings, and both intra- and interobserver variability, in a large group of healthy subjects.METHODS. In a prospective study of 228 eyes, IOP measurements by GAT and DCT were compared, and the effects of central corneal thickness (CCT), corneal curvature, axial length, and anterior chamber depth were analyzed. To evaluate intra- and interobserver variability, IOP was measured in eight eyes by four observers.RESULTS. There was a high concordance between the IOP readings obtained by DCT and GAT. However, IOP readings were consistently higher with DCT than with GAT ( median difference: + 1.7 mm Hg, interquartile range [25th - 75th percentile] = 0.8 - 2.7 mm Hg). In contrast to GAT, multivariable regression analysis showed no significant effect of corneal thickness, corneal curvature, astigmatism, anterior chamber depth, and axial length on DCT readings. For repeated measurements the intraobserver variability was 0.65 mm Hg for the DCT and 1.1 mm Hg for the GAT ( P = 0.008). Interobserver variability was 0.44 mm Hg for the DCT and 1.28 mm Hg for the GAT ( P = 0.017).CONCLUSIONS. IOP measurements by DCT are highly concordant with IOP readings obtained from GAT but do not vary in CCT and have a lower intra- and interobserver variability. DCT seems to be an appropriate method of tonometry for routine clinical use.