Complete genome sequence of Streptomyces reticuli, an efficient degrader of crystalline cellulose.
Complete genome sequence of Streptomyces reticuli, an efficient degrader of crystalline cellulose.
复制标题
DOI：
10.1016/j.jbiotec.2016.02.002
复制
发表时间：
2016-03
影响因子：
4.1
通讯作者：
D. Wibberg;Arwa Al-Dilaimi;T. Busche;Ina Wedderhoff;H. Schrempf;J. Kalinowski;D. Ortiz de Orué Lucana
中科院分区：
文献类型：
--
作者：
D. Wibberg;Arwa Al-Dilaimi;T. Busche;Ina Wedderhoff;H. Schrempf;J. Kalinowski;D. Ortiz de Orué Lucana
我们报道了黑色素产生菌Streptomyces reticuliTü 45（S. reticuli），其通过一系列生物化学表征的蛋白质的协同作用靶向并降解高度结晶的纤维素。它由一条8.3Mb的线性染色体、一个0.8Mb的线性大质粒、一个94kb的线性质粒和一个76kb的环状质粒组成。值得注意的是，巨质粒是已知的第二大链霉菌质粒。初步分析显示，除其他外，43个预测的基因簇的次级代谢产物的合成和456个预测的基因结合和降解纤维素，其他多糖和含碳水化合物。
We report the complete, GC-rich genome sequence of the melanin producerStreptomyces reticuliTü 45 (S. reticuli) that targets and degrades highly crystalline cellulose by the concerted action of a range of biochemically characterized proteins. It consists of a linear 8.3 Mb chromosome, a linear 0.8 Mb megaplasmid, a linear 94 kb plasmid and a circular 76 kb plasmid. Noteworthy, the megaplasmid is the second largest knownStreptomycesplasmid. Preliminary analysis reveals, among others, 43 predicted gene clusters for the synthesis of secondary metabolites and 456 predicted genes for binding and degradation of cellulose, other polysaccharides and carbohydrate-containing compounds.