Oximeter studies on patients with chronic obstructive emphysema, awake and during sleep.
Oximeter studies on patients with chronic obstructive emphysema, awake and during sleep.
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对慢性阻塞性肺气肿患者清醒时和睡眠时的血氧计研究。
DOI：
10.1056/nejm196203292661303
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发表时间：
1962
期刊：
影响因子：
--
通讯作者：
E. Cree
中科院分区：
文献类型：
--
作者：
C. Trask;E. Cree
患有晚期阻塞性肺气肿住院的患者通常会感到紧张、焦虑和紧张，甚至比普通住院患者的程度可能更严重。由于呼吸困难和咳嗽，他们往往睡眠质量不佳，并且经常需要在夜间使用镇静剂。不应使用镇静剂，因为抑制呼吸中枢会减少通气量并进一步减少气体交换。正常人睡眠期间通气会发生变化。如果伴有缺氧的晚期阻塞性肺气肿患者在睡眠时动脉血氧饱和度进一步下降，则禁忌使用镇静剂，夜间氧疗可能成为治疗的重要辅助手段。 。 。 。
PATIENTS hospitalized with advanced obstructive emphysema are often nervous, anxious and tense, perhaps to a greater degree than the average hospital patient. Because of dyspnea and cough they tend to sleep poorly and often request sedatives for use at night. Sedatives should not be administered, for respiratory-center depression will reduce ventilatory effort and further decrease gas exchange. Alterations in ventilation occur during sleep in normal persons. If patients with advanced obstructive emphysema associated with hypoxia have a further fall in arterial oxygen saturation during sleep, sedatives are contraindicated, and oxygen therapy at night might become an important adjunct to treatment. . . .