IDENTIFICATION OF A MEMBRANE GLYCOPROTEIN ASSOCIATED WITH HEMATOPOIETIC PROGENITOR CELLS
IDENTIFICATION OF A MEMBRANE GLYCOPROTEIN ASSOCIATED WITH HEMATOPOIETIC PROGENITOR CELLS
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DOI：
10.1016/0145-2126(85)90082-7
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发表时间：
1985-01-01
影响因子：
2.7
通讯作者：
GREAVES, MF
中科院分区：
文献类型：
--
作者：
KATZ, FE;TINDLE, R;GREAVES, MF
描述了一种选择性结合人骨髓和胎儿肝脏祖细胞群的单克隆抗体（3C5）。成熟的淋巴细胞（T、B）集落形成细胞不表达抗原。该抗体鉴定出一种细胞表面糖蛋白。100,000可能在早期造血分化中具有重要的调节作用。
A monoclonal antibody (3C5) is described which selectively binds to progenitor cell populations in human bone marrow and fetal liver. Mature, lymphoid (T,B) colony forming cells do not express the antigen. The antibody identifies a cell surface glycoprotein of MW .apprx. 100,000 which might have an important regulatory role in early hemopoietic differentiation.