Identification of human RNA editing sites: A historical perspective.
Identification of human RNA editing sites: A historical perspective.
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DOI:
10.1016/j.ymeth.2016.05.011
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发表时间:
2016-09-01
期刊:
影响因子:
4.8
通讯作者:
Li, Jin Billy
中科院分区:
文献类型:
--
作者:
Ramaswami, Gokul;Li, Jin Billy
A-to-I RNA editing is an essential gene regulatory mechanism. Once thought to be a rare phenomenon only occurring in a few transcripts, the emergence of high-throughput RNA sequencing has facilitated the identification of over 2 million RNA editing sites in the human transcriptome. In this review, we survey the current RNA-seq based methods as well as historical methods used to identify RNA editing sites.
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