Physical growth and neurodevelopmental outcome of nonhandicapped low-risk children born preterm
Physical growth and neurodevelopmental outcome of nonhandicapped low-risk children born preterm
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DOI：
10.1016/j.earlhumdev.2004.05.001
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发表时间：
2004-09-01
影响因子：
2.5
通讯作者：
Linderkamp, O
中科院分区：
文献类型：
--
作者：
Pietz, J;Peter, J;Linderkamp, O
背景资料：关于早产影响的结果研究越来越局限于出生体重低于1000克或胎龄低于26周的极不成熟婴儿。相比之下，包括低风险早产儿的研究是罕见的。目的：为了检查生长和神经发育的结果，70低风险低出生体重（LBW）的儿童没有神经功能障碍，从出生到7岁。在7岁时，LBW儿童进行了比较，在term.Methods出生的匹配对照组：出生后的生长测定在20个月的LBW组和7年的LBW和对照组儿童。在20个月时，使用Griffiths量表对LBW组进行评估。在7岁时，LBW和对照组儿童进行了评估与神经心理学测试电池，包括测试语言，视觉知觉，视觉运动，精细和粗大的运动能力。
Background: Outcome studies on the effects of prematurity are increasingly restricted to extremely immature infants with birth weight below 1000 g or gestational age below 26 weeks. In contrast, studies comprising low-risk preterm infants are rare.Aim: To examine growth and neurodevelopmental outcome, 70 low-risk low birth weight (LBW) children without neurological impairment were followed from birth to 7 years of age. At 7 years of age, LBW children were compared to a matched control group born at term.Methods: Postnatal growth was measured at 20 months in the LBW group and at 7 years in LBW and control children. At 20 months, the LBW group was assessed with the Griffiths Scales. At 7 years, LBW and control children were assessed with a neuropsychological test battery comprising tests for language, visual-perceptual, visual-motor, fine and gross motor abilities.Results: At 7 years of age, the frequency of children with low (3rd-9th percentile) or subnormal (