Do mass deworming efforts improve the developmental health and well-being of children in low- and middle-income countries? Summary of the evidence and implications for public health programmes
Do mass deworming efforts improve the developmental health and well-being of children in low- and middle-income countries? Summary of the evidence and implications for public health programmes
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DOI：
10.1016/j.cegh.2018.09.004
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发表时间：
2018-12-01
影响因子：
2.6
通讯作者：
Issac, Anns
中科院分区：
文献类型：
--
作者：
John, Denny;Issac, Anns
目的：本坎贝尔系统综述的证据总结评估了大规模驱虫对土壤传播蠕虫的有效性，同时进行或不进行血吸虫病驱虫或联合干预对儿童的生长、教育成就、认知、入学率、生活质量和不良反应的影响，这些研究来自随机试验、准随机试验、前后对照研究、中断时间序列和准实验研究。证据总结采用标准方法进行和报告证据总结，并使用SUPPORT总结格式。结果：坎贝尔审查包括来自66项研究的数据，涉及23个低收入和中等收入国家的高、中、低蠕虫流行地区的1，092，120名儿童（6个月-16岁）。与以前的审查主题相比，目前审查的不同结论是由于纳入更多的研究和通过一个严格的标准，为certainty of evidence.Conclusion：审查发现，大规模驱虫土壤传播的蠕虫对儿童健康和其他福利措施几乎没有影响。
Objective: This evidence summary of a Campbell systematic review evaluated the effectiveness of mass deworming for soil transmitted helminthes with or without deworming for schistosomiasis or co-interventions on growth, educational achievement, cognition, school attendance, quality of life and adverse effects in children from randomized trials, quasi-randomized trials, controlled before after studies, interrupted time series and quasi-experimental studies.Methods: Summary of evidence was prepared using standard methods for conducting and reporting evidence summary and using SUPPORT summary format.Results: The Campbell review included data from 66 studies covering 1,092,120 children (6 months-16 years) in high, medium, and low helminthes-endemic areas from 23 low and middle-income countries. As compared to previous reviews on the topic, the different conclusions of current review are due to inclusion of more studies and adoption of a strict criterion for the certainty of evidence.Conclusion: The review found that mass deworming for soil transmitted helminthes had little to no effect on child health and other well-being measures.