Phenylazonaphthalene as a superb photo-regulator for DNA-triplex formation

Phenylazonaphthalene as a superb photo-regulator for DNA-triplex formation
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DOI:
10.1016/s0040-4039(01)01347-8
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发表时间:
2001-09-17
影响因子:
1.8
通讯作者:
Komiyama, M
Komiyama, M
中科院分区:
化学4区
文献类型:
--
作者:
Liang, XG;Asanuma, H;Komiyama, M

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将苯基偶氮萘连接到oligo(T)的5 '端,作为光响应部分,用于光调节DNA三链体的形成。苯偶氮萘的反-顺异构化使DNA-三链体的解链温度发生了40.5 ℃的变化。这种变化比偶氮苯所实现的变化大得多。(C)2001爱思唯尔科技有限公司版权所有。
Phenylazonaphthalene was tethered to the 5'-end of oligo(T) as photo-responsive moiety for the photo-regulation of DNA-triplex formation. The melting temperature of DNA-triplex changed as greatly as 40.5 degreesC on trans cis isomerization of phenylazonaphthalene. This change was much greater than that achieved by azobenzene. (C) 2001 Elsevier Science Ltd. All rights reserved.