Predicting the orientation of invisible stimuli from activity in human primary visual cortex
Predicting the orientation of invisible stimuli from activity in human primary visual cortex
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DOI：
10.1038/nn1445
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发表时间：
2005-05-01
影响因子：
25
通讯作者：
Rees, G
中科院分区：
文献类型：
--
作者：
Haynes, JD;Rees, G
人类可以体验到无意识感知的定向刺激的后效，这表明这些刺激会接受皮层处理。确定这种影响的生理基板已被证明是难以捉摸的，由于传统的人类神经成像技术的空间分辨率较低的视觉皮层中的方向列的大小相比。在这里，我们表明，即使在传统的分辨率，它是可以使用功能磁共振成像，以获得一个方向选择性处理V1的直接措施。我们发现，V1的许多部分显示出对定向刺激的微妙但可重复的偏见，并且我们可以使用多变量模式识别在整个V1中积累这些信息。利用这些信息，我们可以成功地预测参与者正在观看两个定向刺激中的哪一个，即使掩蔽使刺激不可见。我们的研究结果表明，传统的功能磁共振成像可以用来揭示人类大脑皮层的功能选择性处理，即使是不可见的刺激。
Humans can experience aftereffects from oriented stimuli that are not consciously perceived, suggesting that such stimuli receive cortical processing. Determining the physiological substrate of such effects has proven elusive owing to the low spatial resolution of conventional human neuroimaging techniques compared to the size of orientation columns in visual cortex. Here we show that even at conventional resolutions it is possible to use fMRI to obtain a direct measure of orientation-selective processing in V1. We found that many parts of V1 show subtle but reproducible biases to oriented stimuli, and that we could accumulate this information across the whole of V1 using multivariate pattern recognition. Using this information, we could then successfully predict which one of two oriented stimuli a participant was viewing, even when masking rendered that stimulus invisible. Our findings show that conventional fMRI can be used to reveal feature-selective processing in human cortex, even for invisible stimuli.