Hierarchical signaling transduction of the immune and muscle cell crosstalk in muscle regeneration
Hierarchical signaling transduction of the immune and muscle cell crosstalk in muscle regeneration
复制标题
肌肉再生中免疫和肌肉细胞串扰的分层信号转导
DOI：
10.1016/j.cellimm.2017.08.006
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发表时间：
2017
影响因子：
4.3
通讯作者：
Ping Hu
中科院分区：
文献类型：
--
作者：
Wenjun Yang;Ping Hu
肌肉再生是一个复杂的生物过程，涉及多种细胞类型，包括坏死肌肉。细胞，卫星细胞，间充质细胞，周细胞，免疫细胞和其他细胞类型存在于损伤部位。免疫细胞参与先天性和适应性免疫反应调节肌肉再生的进程。在这篇综述中，我们讨论了不同的免疫细胞在肌肉再生中的作用。免疫。细胞通过细胞因子产生、细胞间接触和一般免疫环境调节来调节肌肉再生。我们还描述了目前已知的免疫细胞如何调节肌肉再生的机制。
The muscle regeneration is a complicated bioprocess that involved in many cell types, including necrotic muscle.cells, satellite cells, mesenchymal cells, pericytes, immune cells, and other cell types present at the injury site..Immune cells involved in both innate and adaptive immune responses regulate the progress of muscle regeneration..In this review, we discussed the roles of different immune cells in muscle regeneration. The immune.cells regulate muscle regeneration through cytokine production, cell-cell contacts, and general immune environment.regulation. We also describe the current known mechanism of how immune cells regulating muscle.regeneration.