Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.
Toward a global and reproducible science for brain imaging in neurotrauma: the ENIGMA adult moderate/severe traumatic brain injury working group.
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DOI：
10.1007/s11682-020-00313-7
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发表时间：
2021-04
影响因子：
3.2
通讯作者：
Hillary FG
中科院分区：
文献类型：
--
作者：
Olsen A;Babikian T;Bigler ED;Caeyenberghs K;Conde V;Dams-O'Connor K;Dobryakova E;Genova H;Grafman J;Håberg AK;Heggland I;Hellstrøm T;Hodges CB;Irimia A;Jha RM;Johnson PK;Koliatsos VE;Levin H;Li LM;Lindsey HM;Livny A;Løvstad M;Medaglia J;Menon DK;Mondello S;Monti MM;Newcombe VFJ;Petroni A;Ponsford J;Sharp D;Spitz G;Westlye LT;Thompson PM;Dennis EL;Tate DF;Wilde EA;Hillary FG
创伤性脑损伤（TBI）引起的死亡率和发病率的全球负担是显著的，TBI患者的异质性和目前大多数神经影像学研究的相对较小的样本量是科学进步和临床转化的主要挑战。ENIGMA（Enhancing NeuroImaging Genetics through Meta-Analysis）Adult Moderate/Severe TBI（AMS-TBI）工作组旨在通过为全球研究人员提供大规模跨境合作和数据共享的有效框架和平台，成为AMS-TBI新发现的推动力。基于透明，严谨，可重复性和协作的原则，我们将促进多尺度和大数据分析管道的开发和传播，以便使用结构和功能神经成像结合非成像生物标志物，遗传学以及临床和行为措施来协调AMS-TBI的分析。最终，我们将为研究人员提供一个前所未有的机会，通过利用我们强大的大规模神经影像数据分析方法来测试关于AMS-TBI恢复和发病率的重要假设。在这份共识声明中，我们概述了工作组的短期、中期和长期目标。
The global burden of mortality and morbidity caused by traumatic brain injury (TBI) is significant, and the heterogeneity of TBI patients and the relatively small sample sizes of most current neuroimaging studies is a major challenge for scientific advances and clinical translation. The ENIGMA (Enhancing NeuroImaging Genetics through Meta-Analysis) Adult moderate/severe TBI (AMS-TBI) working group aims to be a driving force for new discoveries in AMS-TBI by providing researchers world-wide with an effective framework and platform for large-scale cross-border collaboration and data sharing. Based on the principles of transparency, rigor, reproducibility and collaboration, we will facilitate the development and dissemination of multiscale and big data analysis pipelines for harmonized analyses in AMS-TBI using structural and functional neuroimaging in combination with non-imaging biomarkers, genetics, as well as clinical and behavioral measures. Ultimately, we will offer investigators an unprecedented opportunity to test important hypotheses about recovery and morbidity in AMS-TBI by taking advantage of our robust methods for large-scale neuroimaging data analysis. In this consensus statement we outline the working group’s short-term, intermediate, and long-term goals.
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影响因子：
4.2
作者：
Brezova, Veronika;Moen, Kent Goran;Haberg, Asta K.
通讯作者：
Haberg, Asta K.
影响因子：
5.3
作者：
Bonnelle, Valerie;Leech, Robert;Sharp, David J.
通讯作者：
Sharp, David J.
影响因子：
5.7
作者：
Caeyenberghs, Karen;Verhelst, Helena;Wilson, Peter H.
通讯作者：
Wilson, Peter H.
DOI：
10.1073/pnas.1409952112
发表时间：
2015-04-21
影响因子：
11.1
作者：
Barrio, Jorge R.;Small, Gary W.;Kepe, Vladimir
通讯作者：
Kepe, Vladimir
DOI：
10.1016/j.nicl.2017.02.002
发表时间：
2017
期刊：
NeuroImage. Clinical
影响因子：
--
作者：
Bodart O;Gosseries O;Wannez S;Thibaut A;Annen J;Boly M;Rosanova M;Casali AG;Casarotto S;Tononi G;Massimini M;Laureys S
通讯作者：
Laureys S