Acupuncture treatment for irritable bowel syndrome - A double-blind controlled study
Acupuncture treatment for irritable bowel syndrome - A double-blind controlled study
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DOI：
10.1159/000048847
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发表时间：
2001-01-01
期刊：
影响因子：
3.2
通讯作者：
Carasso, R
中科院分区：
文献类型：
--
作者：
Fireman, Z;Segal, A;Carasso, R
背景/目的：肠易激综合征是西方社会最常见的胃肠道疾病之一，影响约15%的人口，特别是年轻人。肠易激综合征的病因和有效的治疗方法仍然难以捉摸。本研究采用双盲对照研究方法，通过比较真针与假针对肠易激综合征患者的疗效，探讨针刺的治疗价值。方法：25例符合罗马标准（肠易激综合征症状持续1年以上）的患者组成最终研究人群。他们是通过向在我们医疗中心所在地区执业的胃肠病学家发出的“招募”公告招募的。在LI-4（结肠经，仅针）和BL-60（膀胱经，仅针）进行真针和假针。患者随机分配至两组之一。结果：第一次真针对总体症状和腹痛的影响是明确和显著的改善（p = 0.05）。在第二次会议上没有看到类似的效果。结论：虽然真正的针灸效果一直更好，但在总体统计分析中，两组之间没有发现差异。我们不能证明这种治疗方式在肠易激综合征中的治疗益处。版权所有（C）2001 S. Karger AG，巴塞尔。
Background/Aim: Irritable bowel syndrome is one of the most common gastrointestinal disorders in Western society, affecting around 15% of the population, especially young adults. The cause(s) of irritable bowel syndrome and effective treatment(s) have remained elusive. This study aimed at exploring the therapeutic value of acupuncture by comparing the responses of irritable bowel syndrome sufferers to true acupuncture versus sham acupuncture in a controlled double-blind study. Methods:Twenty-five patients who fulfilled the Rome criteria (irritable bowel syndrome symptoms persisting for more than 1 year) comprised the final study population. They were recruited through a 'call for' bulletin sent to gastroenterologists practicing in the region of our medical center. True acupuncture was performed at LI-4 (colonic meridian, needle only) and sham acupuncture at BL-60 (urinary vesicle meridian, needle only). Patient assignment to one of the two groups was random. Results:The effect of the first true acupuncture on overall symptoms and abdominal pain was a clear and significant improvement (p = 0.05). No comparable effect was seen in the second session. Conclusions: Although the true acupuncture results were consistently better, no difference was found between the two groups in the overall statistical analysis. We could not show a therapeutic benefit of this treatment modality in irritable bowel syndrome. Copyright (C) 2001 S. Karger AG, Basel.