Efficacy of the BioXtra dry mouth care system in the treatment of radiotherapy-induced xerostomia
Efficacy of the BioXtra dry mouth care system in the treatment of radiotherapy-induced xerostomia
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DOI：
10.1007/s00520-006-0210-y
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发表时间：
2007-12-01
影响因子：
3.1
通讯作者：
Van den Bogaert, Walter
中科院分区：
文献类型：
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作者：
Dirix, Piet;Nuyts, Sandra;Van den Bogaert, Walter
前言口干症是头颈部肿瘤放射治疗的常见并发症。对症治疗包括严格的口腔卫生以防止口腔感染和唾液替代品以增加舒适性。材料与方法对34例放射性口干症患者在使用BioXtra保湿凝胶、牙膏和漱口水治疗4周前和治疗后4周分别进行口干症状评分、生活质量(QOL)调查和视觉模拟评分(VAS)调查。治疗开始时平均VAS评分为59.8分。治疗后降至36.4(p<0.05)。
Introduction Xerostomia is a common complication of radiotherapy for head and neck cancer. Symptomatic treatment consists of stringent oral hygiene to prevent oral infections and saliva substitutes to increase comfort. The aim of the study was to evaluate the clinical effectiveness of the BioXtra (BX) dry mouth care system.Materials and methods A xerostomia questionnaire consisting of 3 parts (xerostomia symptom score, quality of life (QoL) survey and visual analogue scale (VAS)) was completed by 34 patients suffering from radiation-induced xerostomia, before and after 4 weeks of treatment with the BioXtra moisturizing gel, toothpaste and mouthwash.Results The BioXtra products significantly diminished the most common symptoms of xerostomia. Mean VAS score at the start of treatment was 59.8. After treatment, this decreased to 36.4 (p